Dr. Ben Bikman

start beating this drum of saturated fats and use it as evidence against animal products because animal products do contain saturated fats invariably. Now, they're never completely saturated fat, and that's important. There's a mix of saturated mono and polyunsaturated fats. And by the way, all saturated fats aren't the same.

Oh, my gosh. Yeah. There's dozens of them. Yeah, that's right. I'm a huge advocate of a full spectrum of fats, namely of saturated fats, even long chain, which we get a lot of medium chain and then short chain.

Oh, my gosh. Yeah. There's dozens of them. Yeah, that's right. I'm a huge advocate of a full spectrum of fats, namely of saturated fats, even long chain, which we get a lot of medium chain and then short chain.

Oh, my gosh. Yeah. There's dozens of them. Yeah, that's right. I'm a huge advocate of a full spectrum of fats, namely of saturated fats, even long chain, which we get a lot of medium chain and then short chain.

Putting that to the side there, when you incubate a cell, if you have a cell culture, whether it is muscle cells, liver cells, neurons, fat cells, and if you incubate those fat cells with palmitic acid, which is the prevalent saturated fat in the human body, certainly in circulation, palmitate or the 16 carbon saturated fat.

Putting that to the side there, when you incubate a cell, if you have a cell culture, whether it is muscle cells, liver cells, neurons, fat cells, and if you incubate those fat cells with palmitic acid, which is the prevalent saturated fat in the human body, certainly in circulation, palmitate or the 16 carbon saturated fat.

Putting that to the side there, when you incubate a cell, if you have a cell culture, whether it is muscle cells, liver cells, neurons, fat cells, and if you incubate those fat cells with palmitic acid, which is the prevalent saturated fat in the human body, certainly in circulation, palmitate or the 16 carbon saturated fat.

When you incubate cells with palmitate or stearate acid even, 18 carbons, they will become insulin resistant. And so you treat them with the fats. Then you put on some insulin a little later and then measure. Then you take all the cells and measure what insulin did. And it is compromised. That doesn't happen when you incubate the cells with monounsaturated or polyunsaturated fats.

When you incubate cells with palmitate or stearate acid even, 18 carbons, they will become insulin resistant. And so you treat them with the fats. Then you put on some insulin a little later and then measure. Then you take all the cells and measure what insulin did. And it is compromised. That doesn't happen when you incubate the cells with monounsaturated or polyunsaturated fats.

When you incubate cells with palmitate or stearate acid even, 18 carbons, they will become insulin resistant. And so you treat them with the fats. Then you put on some insulin a little later and then measure. Then you take all the cells and measure what insulin did. And it is compromised. That doesn't happen when you incubate the cells with monounsaturated or polyunsaturated fats.

that it will not cause direct cellular insulin resistance. So I've done these studies myself. Maybe the most cited study of mine I've ever done was this exact series of studies. And the same thing happens in rodents.

that it will not cause direct cellular insulin resistance. So I've done these studies myself. Maybe the most cited study of mine I've ever done was this exact series of studies. And the same thing happens in rodents.

that it will not cause direct cellular insulin resistance. So I've done these studies myself. Maybe the most cited study of mine I've ever done was this exact series of studies. And the same thing happens in rodents.

When you infuse the rodent with fat, when you're infusing it directly IV, the saturated fat will cause insulin resistance, but the monounsaturated, like olive oil, for example, doesn't. So there is a direct effect of saturated fats at the cell to cause insulin resistance.

When you infuse the rodent with fat, when you're infusing it directly IV, the saturated fat will cause insulin resistance, but the monounsaturated, like olive oil, for example, doesn't. So there is a direct effect of saturated fats at the cell to cause insulin resistance.

When you infuse the rodent with fat, when you're infusing it directly IV, the saturated fat will cause insulin resistance, but the monounsaturated, like olive oil, for example, doesn't. So there is a direct effect of saturated fats at the cell to cause insulin resistance.

And this is all, once you actually get into the cell itself, it's because of how these fats will induce the accumulation of another molecule called ceramides. And if anyone has ever heard ceramides in the audience, they might be thinking of it as like in lotions or shampoos and stuff. But it is a slightly different version of it.

And this is all, once you actually get into the cell itself, it's because of how these fats will induce the accumulation of another molecule called ceramides. And if anyone has ever heard ceramides in the audience, they might be thinking of it as like in lotions or shampoos and stuff. But it is a slightly different version of it.

And this is all, once you actually get into the cell itself, it's because of how these fats will induce the accumulation of another molecule called ceramides. And if anyone has ever heard ceramides in the audience, they might be thinking of it as like in lotions or shampoos and stuff. But it is a slightly different version of it.

But saturated fats will induce the accumulation of these molecules called ceramides within a cell. Then ceramides will directly prevent insulin, the insulin biochemical pathway from doing its job. It directly antagonizes what insulin is trying to do. So that's the actual where the rubber meets the road molecular mediator.