Dr. Ben Bikman

But saturated fats will induce the accumulation of these molecules called ceramides within a cell. Then ceramides will directly prevent insulin, the insulin biochemical pathway from doing its job. It directly antagonizes what insulin is trying to do. So that's the actual where the rubber meets the road molecular mediator.

But saturated fats will induce the accumulation of these molecules called ceramides within a cell. Then ceramides will directly prevent insulin, the insulin biochemical pathway from doing its job. It directly antagonizes what insulin is trying to do. So that's the actual where the rubber meets the road molecular mediator.

So now to zoom back out to the level of the whole body, some people look at those studies, even possibly my own, and will use that as evidence against saturated fat. And they will say, see, saturated fat causes insulin resistance, but... It doesn't work.

So now to zoom back out to the level of the whole body, some people look at those studies, even possibly my own, and will use that as evidence against saturated fat. And they will say, see, saturated fat causes insulin resistance, but... It doesn't work.

So now to zoom back out to the level of the whole body, some people look at those studies, even possibly my own, and will use that as evidence against saturated fat. And they will say, see, saturated fat causes insulin resistance, but... It doesn't work.

When you actually go to the whole body and look at the consumption of fat, the paradox is the vast majority, overwhelming majority of saturated fat in our blood is palmitate, but it's not from the diet. It comes from the liver. The liver is the primary source of saturated fats that are circulating in the blood.

When you actually go to the whole body and look at the consumption of fat, the paradox is the vast majority, overwhelming majority of saturated fat in our blood is palmitate, but it's not from the diet. It comes from the liver. The liver is the primary source of saturated fats that are circulating in the blood.

When you actually go to the whole body and look at the consumption of fat, the paradox is the vast majority, overwhelming majority of saturated fat in our blood is palmitate, but it's not from the diet. It comes from the liver. The liver is the primary source of saturated fats that are circulating in the blood.

When we eat saturated fats, they're packaged into the chylomicron, and there can be some depositing of that throughout the body, but it goes to the liver, and then the liver will repackage all that fat. Almost always, the saturated fats will have two things happen to them. They get elongated by two carbons, so you'll take that 16-carbon palmitate, which is the most prevalent saturated fat.

When we eat saturated fats, they're packaged into the chylomicron, and there can be some depositing of that throughout the body, but it goes to the liver, and then the liver will repackage all that fat. Almost always, the saturated fats will have two things happen to them. They get elongated by two carbons, so you'll take that 16-carbon palmitate, which is the most prevalent saturated fat.

When we eat saturated fats, they're packaged into the chylomicron, and there can be some depositing of that throughout the body, but it goes to the liver, and then the liver will repackage all that fat. Almost always, the saturated fats will have two things happen to them. They get elongated by two carbons, so you'll take that 16-carbon palmitate, which is the most prevalent saturated fat.

We take that 60 carbon, we make it into an 18 carbon, and then we desaturate it. There are these two steps. And so we end up taking the palmitate in the diet and turning it into oleic acid or the primary fat. Olive oil. Olive oil. And that is the primary fat that is stored in every single person's fat cells.

We take that 60 carbon, we make it into an 18 carbon, and then we desaturate it. There are these two steps. And so we end up taking the palmitate in the diet and turning it into oleic acid or the primary fat. Olive oil. Olive oil. And that is the primary fat that is stored in every single person's fat cells.

We take that 60 carbon, we make it into an 18 carbon, and then we desaturate it. There are these two steps. And so we end up taking the palmitate in the diet and turning it into oleic acid or the primary fat. Olive oil. Olive oil. And that is the primary fat that is stored in every single person's fat cells.

No, no, no. So the fat cells turn it into olive oil, but the liver makes palmitate. Yeah, yeah. So when we eat saturated fats, the body will turn it into olive oil, basically. But when the liver is making fat, it makes saturated fats.

No, no, no. So the fat cells turn it into olive oil, but the liver makes palmitate. Yeah, yeah. So when we eat saturated fats, the body will turn it into olive oil, basically. But when the liver is making fat, it makes saturated fats.

No, no, no. So the fat cells turn it into olive oil, but the liver makes palmitate. Yeah, yeah. So when we eat saturated fats, the body will turn it into olive oil, basically. But when the liver is making fat, it makes saturated fats.

And so this is why you can take someone and put them on a ketogenic diet, low carb, high fat, and they could be eating three times more saturated fat than the other group, than the low fat, high carb group. Three times more saturated fat. And yet the actual composition of fatty acids in their lipoproteins in their blood is much less saturated.

And so this is why you can take someone and put them on a ketogenic diet, low carb, high fat, and they could be eating three times more saturated fat than the other group, than the low fat, high carb group. Three times more saturated fat. And yet the actual composition of fatty acids in their lipoproteins in their blood is much less saturated.

And so this is why you can take someone and put them on a ketogenic diet, low carb, high fat, and they could be eating three times more saturated fat than the other group, than the low fat, high carb group. Three times more saturated fat. And yet the actual composition of fatty acids in their lipoproteins in their blood is much less saturated.