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Dr. Brad McGregor

๐Ÿ‘ค Speaker
290 total appearances

Appearances Over Time

Podcast Appearances

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

It doesn't change my management in the perioperative setting today.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

Again, I get it in that perioperative setting because I'm worried they're going to relapse.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

I want to have the information in the future should they need it.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

But I don't think we had any data that we can sort of offer patients some this or that based on some, like, change what treatment we're using based on that.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

Yeah, I agree.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

I actually expect the data in the cis-eligible population to look markedly better, actually, than we saw in the style, only because you get four cycles in the pre-op map, there's three cycles.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

And if you just look at EV in the metastatics, EV per metastatics, and the patients with cisplatin ineligible had a better outcome, right?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

So they're just fitter patients, better tolerability, all the therapies, so...

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

I actually, I do think it's super positive.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

And so to that point, I mean, yes, I think, you know, I'm looking for reasons for patients to be cisplatin ineligible in the current era.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

You know, I have very, I have patients that have been online coming in, right?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

So they're already asking, like, well, can I...

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

What about ED Pembroke?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

I saw this.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

I saw this online.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

I saw this here, that.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

And so I think it's important to have that realistic discussion with the patient.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

Like, you know, in a metastatic setting, ED Pembroke beat platinum therapy.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

It beat cisplatin.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

It beat carboplatin.