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Dr. Casey Means

๐Ÿ‘ค Speaker
1139 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

they know what their glucose is.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And so they're never going to walk into a doctor's office and have a bomb dropped on them about prediabetes or type 2 diabetes because you have the data, which is ultimately, I hope, the world that we can move towards for a lot of biomarkers.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

So you can see trends over time, which I think is very valuable.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

One thing that's fascinating in terms of early prediction of metabolic disease is that you can see how long it takes your glucose to come down after a meal.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

So

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

In a normal, healthy, insulin-sensitive body, even if the glucose goes way up, it should come way down very quickly because the insulin is binded to insulin receptors and the glucose is getting taken up and it'll lower.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

What is quickly over the course of- It should be down by two hours.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

But from what I've actually seen in our most insulin-sensitive people and also in research that looks at young, healthy populations, you should basically be spiking and coming down, spike about 45 minutes and come down hour and a half, 90 minutes to two hours.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

But if-

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

After last bite, although it's hard to kind of exactly know.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

But yeah, meal is over.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

I would say about 45 minutes to go up to the peak and then start coming down very quickly.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

Now, if you start to see that glucose is going up and then trailing very slowly back down to normal, maybe taking more than two hours, three hours,

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

that is going to be one of those early indicators of potential insulin resistance.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

Your body's not clearing the glucose, but that's not a metric that we use in standard practice.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

At all.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And I've actually seen myself very insulin sensitive.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

My insulin is like 2.5.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And, you know, if I don't sleep and I am stressed and I have been sitting, my glucose will take way longer to come down.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

I have become transiently insulin resistant.