Dr. Christopher Gardner
๐ค SpeakerAppearances Over Time
Podcast Appearances
So we shared it with the company, and they said, well, I can see you're saying there's a null finding here, but could you also say there was no deleterious effect? And I said, we weren't looking for a deleterious effect. We were looking for an improvement. They said, yeah, but isn't it also true that it didn't make it worse? I thought, That's actually true. It didn't make it worse.
Could I, to make these guys happy and to maybe get more money later, should we say it didn't make it worse? So that would be a really subtle influence that they could have later on.
Could I, to make these guys happy and to maybe get more money later, should we say it didn't make it worse? So that would be a really subtle influence that they could have later on.
Could I, to make these guys happy and to maybe get more money later, should we say it didn't make it worse? So that would be a really subtle influence that they could have later on.
And at the end of the day, really, the important thing is to look at the study design. So let me โ I think I can flip this to something that's way more practical than that. It's not even industry influence. It's the investigator influence. So in my world of nutrition โ and this is going to go back to the parking lot of not doing one thing at one time but doing multiple things at one time.
And at the end of the day, really, the important thing is to look at the study design. So let me โ I think I can flip this to something that's way more practical than that. It's not even industry influence. It's the investigator influence. So in my world of nutrition โ and this is going to go back to the parking lot of not doing one thing at one time but doing multiple things at one time.
And at the end of the day, really, the important thing is to look at the study design. So let me โ I think I can flip this to something that's way more practical than that. It's not even industry influence. It's the investigator influence. So in my world of nutrition โ and this is going to go back to the parking lot of not doing one thing at one time but doing multiple things at one time.
Let's say I want to study vegan or paleo or keto or something like that. I can have diet A versus diet B and make a kick-ass diet A and a crappy diet B. So it's really unlikely that B will win. And then I publish that and there's a headline on it. And then there's someone else who actually favors a competing diet. They start a study.
Let's say I want to study vegan or paleo or keto or something like that. I can have diet A versus diet B and make a kick-ass diet A and a crappy diet B. So it's really unlikely that B will win. And then I publish that and there's a headline on it. And then there's someone else who actually favors a competing diet. They start a study.
Let's say I want to study vegan or paleo or keto or something like that. I can have diet A versus diet B and make a kick-ass diet A and a crappy diet B. So it's really unlikely that B will win. And then I publish that and there's a headline on it. And then there's someone else who actually favors a competing diet. They start a study.
They make a kick-ass diet B and a crappy diet A. And the diet B wins because they set it up that way. No industry influence at all here. This is investigator influence. And then the public comes and says, what the hell? It said diet A is better one day, and it said diet B is better the next. My God, you nutrition scientists never agree on anything. I was going to go have a burger. I was like, ah.
They make a kick-ass diet B and a crappy diet A. And the diet B wins because they set it up that way. No industry influence at all here. This is investigator influence. And then the public comes and says, what the hell? It said diet A is better one day, and it said diet B is better the next. My God, you nutrition scientists never agree on anything. I was going to go have a burger. I was like, ah.
They make a kick-ass diet B and a crappy diet A. And the diet B wins because they set it up that way. No industry influence at all here. This is investigator influence. And then the public comes and says, what the hell? It said diet A is better one day, and it said diet B is better the next. My God, you nutrition scientists never agree on anything. I was going to go have a burger. I was like, ah.
If you had looked at the design, so one of my favorite new words in nutrition is equipoise. I've been trying to set up studies where it's the best diet A that you could be and the best diet B. So if I can just riff off a couple of things. One of my most famous studies is diet fits. It had to do with a low-carb, low-fat diet, 600 people for a year. This is an $8 million study.
If you had looked at the design, so one of my favorite new words in nutrition is equipoise. I've been trying to set up studies where it's the best diet A that you could be and the best diet B. So if I can just riff off a couple of things. One of my most famous studies is diet fits. It had to do with a low-carb, low-fat diet, 600 people for a year. This is an $8 million study.
If you had looked at the design, so one of my favorite new words in nutrition is equipoise. I've been trying to set up studies where it's the best diet A that you could be and the best diet B. So if I can just riff off a couple of things. One of my most famous studies is diet fits. It had to do with a low-carb, low-fat diet, 600 people for a year. This is an $8 million study.
Yeah. And I told the dieticians, I said, I don't really care which one wins. We actually think there's some genetic predisposition or metabolic predisposition. It'd be great if everybody won. But just to test this fairly, I want all the dieticians to be advising the 600 people in this study. You have to teach both low-fat and low-carb. You get assigned to different groups.
Yeah. And I told the dieticians, I said, I don't really care which one wins. We actually think there's some genetic predisposition or metabolic predisposition. It'd be great if everybody won. But just to test this fairly, I want all the dieticians to be advising the 600 people in this study. You have to teach both low-fat and low-carb. You get assigned to different groups.
Yeah. And I told the dieticians, I said, I don't really care which one wins. We actually think there's some genetic predisposition or metabolic predisposition. It'd be great if everybody won. But just to test this fairly, I want all the dieticians to be advising the 600 people in this study. You have to teach both low-fat and low-carb. You get assigned to different groups.
And teach the best low-carb you can and the best low-fat you can so that if one wins at the end, we can say we gave both of them a fair shot. When we did swap meat, this is the study with appetizing plant food, a meat eating alternative trial, swap meat trial with Beyond Meat. What should we pick for the red meat? Should we pick fast food?