Dr. Christopher Gardner
๐ค SpeakerAppearances Over Time
Podcast Appearances
If we had a high quality of low carb and low fat, we assumed that the average difference would be negligible based on our past work. But we would get this range and we did. This time, somebody had lost 60 pounds and somebody had gained 20 in both groups. And it was a continuum. It's like, oh. This is perfect.
If we had a high quality of low carb and low fat, we assumed that the average difference would be negligible based on our past work. But we would get this range and we did. This time, somebody had lost 60 pounds and somebody had gained 20 in both groups. And it was a continuum. It's like, oh. This is perfect.
If we had a high quality of low carb and low fat, we assumed that the average difference would be negligible based on our past work. But we would get this range and we did. This time, somebody had lost 60 pounds and somebody had gained 20 in both groups. And it was a continuum. It's like, oh. This is perfect.
We are going to have a chance to explain this variability with an oral glucose tolerance test, which is sort of state-of-the-art other than the steady-state plasma glucose thing Jerry Riven does, which is too intense and too expensive. Oral glucose tolerance test, much better than a fasting glucose. And we'll genotype them. And Neither of them predicted the variability.
We are going to have a chance to explain this variability with an oral glucose tolerance test, which is sort of state-of-the-art other than the steady-state plasma glucose thing Jerry Riven does, which is too intense and too expensive. Oral glucose tolerance test, much better than a fasting glucose. And we'll genotype them. And Neither of them predicted the variability.
We are going to have a chance to explain this variability with an oral glucose tolerance test, which is sort of state-of-the-art other than the steady-state plasma glucose thing Jerry Riven does, which is too intense and too expensive. Oral glucose tolerance test, much better than a fasting glucose. And we'll genotype them. And Neither of them predicted the variability.
So a postdoc looked at me afterward and said, there are like 50 single nucleotide polymorphisms that have been linked to obesity, and you tested one set of three of them. So that does mean there's 999,999 other genetic problems. probes or tests that you could use, and you've disproved one of them. And I said, yeah. But the insulin resistance one was very popular.
So a postdoc looked at me afterward and said, there are like 50 single nucleotide polymorphisms that have been linked to obesity, and you tested one set of three of them. So that does mean there's 999,999 other genetic problems. probes or tests that you could use, and you've disproved one of them. And I said, yeah. But the insulin resistance one was very popular.
So a postdoc looked at me afterward and said, there are like 50 single nucleotide polymorphisms that have been linked to obesity, and you tested one set of three of them. So that does mean there's 999,999 other genetic problems. probes or tests that you could use, and you've disproved one of them. And I said, yeah. But the insulin resistance one was very popular.
There were a bunch of studies that had done this. And I have to share a really funny comment that Gary Tobes made while we were doing this, because Gary Tobes was involved in NUSI.
There were a bunch of studies that had done this. And I have to share a really funny comment that Gary Tobes made while we were doing this, because Gary Tobes was involved in NUSI.
There were a bunch of studies that had done this. And I have to share a really funny comment that Gary Tobes made while we were doing this, because Gary Tobes was involved in NUSI.
Low carb. So Gary Tobes is a low carb fanatic. And he gives excellent talks. He can riff on and on about data and data and data. But I have to tell you a funny comment that he made as we got to the end of the study. He said, I realized now that you're at the end and you're about to publish it that you screwed up the study. I said, how did I screw up the study?
Low carb. So Gary Tobes is a low carb fanatic. And he gives excellent talks. He can riff on and on about data and data and data. But I have to tell you a funny comment that he made as we got to the end of the study. He said, I realized now that you're at the end and you're about to publish it that you screwed up the study. I said, how did I screw up the study?
Low carb. So Gary Tobes is a low carb fanatic. And he gives excellent talks. He can riff on and on about data and data and data. But I have to tell you a funny comment that he made as we got to the end of the study. He said, I realized now that you're at the end and you're about to publish it that you screwed up the study. I said, how did I screw up the study?
And he said, well, for the low-fat group, you told them not to have added sugar or refined grain. even though those are low fat. And I said, well, yeah, actually we told both groups to have a really healthy diet and added sugar and refined grains aren't healthy.
And he said, well, for the low-fat group, you told them not to have added sugar or refined grain. even though those are low fat. And I said, well, yeah, actually we told both groups to have a really healthy diet and added sugar and refined grains aren't healthy.
And he said, well, for the low-fat group, you told them not to have added sugar or refined grain. even though those are low fat. And I said, well, yeah, actually we told both groups to have a really healthy diet and added sugar and refined grains aren't healthy.
And he said, well, that's going to diminish the chance to see a difference because most people who are eating low carb versus the traditional low fat do better because the low fatters eating high carb are eating added sugar and refined grain. I thought, that's not screwing this study up. That's doing the equipoise thing. Right.
And he said, well, that's going to diminish the chance to see a difference because most people who are eating low carb versus the traditional low fat do better because the low fatters eating high carb are eating added sugar and refined grain. I thought, that's not screwing this study up. That's doing the equipoise thing. Right.