Dr. Christopher Gardner

And he said, well, that's going to diminish the chance to see a difference because most people who are eating low carb versus the traditional low fat do better because the low fatters eating high carb are eating added sugar and refined grain. I thought, that's not screwing this study up. That's doing the equipoise thing. Right.

I saw a lot of literature showing that insulin resistance did suggest that there was a subset of the population that would do better on low-carb than low-fat. And we've actually now followed up on that study with a ketogenic versus a Mediterranean diet study.

I saw a lot of literature showing that insulin resistance did suggest that there was a subset of the population that would do better on low-carb than low-fat. And we've actually now followed up on that study with a ketogenic versus a Mediterranean diet study.

I saw a lot of literature showing that insulin resistance did suggest that there was a subset of the population that would do better on low-carb than low-fat. And we've actually now followed up on that study with a ketogenic versus a Mediterranean diet study.

And in that particular study, the way we set it up is both groups would get a lot of above-ground vegetables, which keto says is okay, avoid added sugar and refined grain, And keto would have no beans, no fruits, no whole grains. And Mediterranean would embrace beans and whole grains and fruits. And so they didn't have a glycosylated hemoglobin difference.

And in that particular study, the way we set it up is both groups would get a lot of above-ground vegetables, which keto says is okay, avoid added sugar and refined grain, And keto would have no beans, no fruits, no whole grains. And Mediterranean would embrace beans and whole grains and fruits. And so they didn't have a glycosylated hemoglobin difference.

And in that particular study, the way we set it up is both groups would get a lot of above-ground vegetables, which keto says is okay, avoid added sugar and refined grain, And keto would have no beans, no fruits, no whole grains. And Mediterranean would embrace beans and whole grains and fruits. And so they didn't have a glycosylated hemoglobin difference.

That was the primary outcome listed on clinicaltrials.gov. The keto diet raised LDL. The keto diet did actually a better job lowering triglycerides than Mediterranean.

That was the primary outcome listed on clinicaltrials.gov. The keto diet raised LDL. The keto diet did actually a better job lowering triglycerides than Mediterranean.

That was the primary outcome listed on clinicaltrials.gov. The keto diet raised LDL. The keto diet did actually a better job lowering triglycerides than Mediterranean.

Yes.

Yes.

Yes.

No, because they did better at wiping out carbs. When you wipe out all your carbs, then those extra carbs don't go into your liver to make triglycerides. Not surprised. And the keto diet was higher in saturated fat, so it raised the LDL.

No, because they did better at wiping out carbs. When you wipe out all your carbs, then those extra carbs don't go into your liver to make triglycerides. Not surprised. And the keto diet was higher in saturated fat, so it raised the LDL.

No, because they did better at wiping out carbs. When you wipe out all your carbs, then those extra carbs don't go into your liver to make triglycerides. Not surprised. And the keto diet was higher in saturated fat, so it raised the LDL.

Yes, and that's the point. So can we go back there for a minute? So to me, that is the point of sort of looking at this equipoise. So when we made the low-carb and the low-fat both healthy— Our primary predictive outcomes, the genotype thing and the insulin resistance didn't work. And what we took home from that message is you could do either one. If you do them in a healthy way, it would be okay.

Yes, and that's the point. So can we go back there for a minute? So to me, that is the point of sort of looking at this equipoise. So when we made the low-carb and the low-fat both healthy— Our primary predictive outcomes, the genotype thing and the insulin resistance didn't work. And what we took home from that message is you could do either one. If you do them in a healthy way, it would be okay.

Yes, and that's the point. So can we go back there for a minute? So to me, that is the point of sort of looking at this equipoise. So when we made the low-carb and the low-fat both healthy— Our primary predictive outcomes, the genotype thing and the insulin resistance didn't work. And what we took home from that message is you could do either one. If you do them in a healthy way, it would be okay.

And when we took it to ketogenic and Mediterranean, they both lowered glycosylated hemoglobin. The keto had a worse effect on LDL, but a better effect on triglycerides. But as we track the adherence, people couldn't adhere to the keto. They couldn't maintain that really low level of carb and the really low level of fat.