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Dr. Craig Koniver

👤 Person
906 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

And you're going to get subcutaneous fat reduction from the ipramarone, visceral fat reduction from the tesamarone, upregulation of the growth hormone receptor from the BPC. It was a wonderful peptide. We kind of labeled it as a fat loss peptide, but people would put on lean muscle mass. They'd sleep better. Their skin would be better. They'd be more durable. Their thought process would be better.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

And you're going to get subcutaneous fat reduction from the ipramarone, visceral fat reduction from the tesamarone, upregulation of the growth hormone receptor from the BPC. It was a wonderful peptide. We kind of labeled it as a fat loss peptide, but people would put on lean muscle mass. They'd sleep better. Their skin would be better. They'd be more durable. Their thought process would be better.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Awesome stuff. And that's where I think that's where we enjoy it is stacking these peptides together. So it's not, again, just one peptide at a time, but able to do it. And that's why, again, working with a compounding pharmacy, we can put these together. So you're only doing one shot a day. You may be doing three to seven peptides, but it's still one shot.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Awesome stuff. And that's where I think that's where we enjoy it is stacking these peptides together. So it's not, again, just one peptide at a time, but able to do it. And that's why, again, working with a compounding pharmacy, we can put these together. So you're only doing one shot a day. You may be doing three to seven peptides, but it's still one shot.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Awesome stuff. And that's where I think that's where we enjoy it is stacking these peptides together. So it's not, again, just one peptide at a time, but able to do it. And that's why, again, working with a compounding pharmacy, we can put these together. So you're only doing one shot a day. You may be doing three to seven peptides, but it's still one shot.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Yes, five days on, two days off, I came up with because of how we would dose growth hormone. So the traditional growth hormone dosing cycle would be five days on, two days off, taken at bedtime. Yeah. And that's where it came up. And then I personally, with patients and myself, I like to take breaks. So even with supplements, I won't take them on the weekends. Yeah.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Yes, five days on, two days off, I came up with because of how we would dose growth hormone. So the traditional growth hormone dosing cycle would be five days on, two days off, taken at bedtime. Yeah. And that's where it came up. And then I personally, with patients and myself, I like to take breaks. So even with supplements, I won't take them on the weekends. Yeah.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Yes, five days on, two days off, I came up with because of how we would dose growth hormone. So the traditional growth hormone dosing cycle would be five days on, two days off, taken at bedtime. Yeah. And that's where it came up. And then I personally, with patients and myself, I like to take breaks. So even with supplements, I won't take them on the weekends. Yeah.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Because I think, again, anything you expose yourself to on a regular basis is going to decrease the potency. We see that with exercise. We see that with food. If you're eating the same food every day, it seems to become less valuable for you. Change it up. We have to throw on the crazy switch every now and then. But change it up. And so then you're going to make it more potent for you.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Because I think, again, anything you expose yourself to on a regular basis is going to decrease the potency. We see that with exercise. We see that with food. If you're eating the same food every day, it seems to become less valuable for you. Change it up. We have to throw on the crazy switch every now and then. But change it up. And so then you're going to make it more potent for you.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Because I think, again, anything you expose yourself to on a regular basis is going to decrease the potency. We see that with exercise. We see that with food. If you're eating the same food every day, it seems to become less valuable for you. Change it up. We have to throw on the crazy switch every now and then. But change it up. And so then you're going to make it more potent for you.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

I do the same thing with supplements. So that just resonates with me, with people, to take a break from stuff.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

I do the same thing with supplements. So that just resonates with me, with people, to take a break from stuff.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

I do the same thing with supplements. So that just resonates with me, with people, to take a break from stuff.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

But what is the rationale of taking CoQ10? So if I can break it down, try to keep it simple. People are familiar with the mitochondria. It's the battery of the cell, these little organelles inside each cell. And they're responsible for doing many things, but primarily making ATP, chemical energy. And so how do we make energy? Well, there's three main ways the body uses it or makes it.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

But what is the rationale of taking CoQ10? So if I can break it down, try to keep it simple. People are familiar with the mitochondria. It's the battery of the cell, these little organelles inside each cell. And they're responsible for doing many things, but primarily making ATP, chemical energy. And so how do we make energy? Well, there's three main ways the body uses it or makes it.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

But what is the rationale of taking CoQ10? So if I can break it down, try to keep it simple. People are familiar with the mitochondria. It's the battery of the cell, these little organelles inside each cell. And they're responsible for doing many things, but primarily making ATP, chemical energy. And so how do we make energy? Well, there's three main ways the body uses it or makes it.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

First is glycolysis. We take glucose, which is a six-carbon molecule. We break it in half to make two pyruvates. When we do that, we make a little bit of ATP. That pyruvate then is converted to something called acetyl-CoA. We run that through the Krebs cycle. where we're also making ATP, but then we're making these intermediate products.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

First is glycolysis. We take glucose, which is a six-carbon molecule. We break it in half to make two pyruvates. When we do that, we make a little bit of ATP. That pyruvate then is converted to something called acetyl-CoA. We run that through the Krebs cycle. where we're also making ATP, but then we're making these intermediate products.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

First is glycolysis. We take glucose, which is a six-carbon molecule. We break it in half to make two pyruvates. When we do that, we make a little bit of ATP. That pyruvate then is converted to something called acetyl-CoA. We run that through the Krebs cycle. where we're also making ATP, but then we're making these intermediate products.