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Huberman Lab

Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

07 Oct 2024

Transcription

Full Episode

0.41 - 23.891 Andrew Huberman

Welcome to the Huberman Lab Podcast, where we discuss science and science-based tools for everyday life. I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine. My guest today is Dr. Craig Conover. Dr. Craig Conover is a medical doctor who did his training at Brown University and Thomas Jefferson University.

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24.451 - 42.288 Andrew Huberman

He is a world expert in what he refers to as performance medicine, which involves the use of peptides and other therapies for improving mental health, physical health, and performance. Now, many of you have perhaps heard of peptide therapies. Perhaps some of you have not. A peptide is simply a small protein. So insulin is a peptide.

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42.508 - 60.071 Andrew Huberman

We have many different thousands of peptides in our brain and body, and they perform a variety of different roles. Dr. Conover's expertise is in the use of exogenous, that is, peptides that one takes, exogenous peptides for activating multiple pathways in the brain and body to augment health.

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60.451 - 79.785 Andrew Huberman

Now, of course, peptides such as insulin have been used for many years now to treat things like diabetes, but today we talk about novel peptides, including GLP-1, so these are glucagon-like peptide analogs, Things like Ozempic and Monjaro, which I realize are a bit controversial. However, today we talk about the micro dosing of those peptides.

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79.825 - 101.458 Andrew Huberman

We talk about those peptides combined with other peptides, as well as behavioral practices to offset the muscle loss associated with them. And then we dive into some lesser known peptides, but ones that are growing in use. For instance, BPC-157 or body protection compound 157, which is used to treat inflammation, to accelerate wound healing and a variety of other things.

101.718 - 122.045 Andrew Huberman

Then we discussed the use of peptides specifically to increase growth hormone secretion during sleep as well as some peptides that can actually increase rapid eye movement sleep dramatically. Today, we also discuss testosterone therapies, not just for men, but for women. These are growing increasingly popular, as well as things like NAD, as well as specific supplements.

122.345 - 140.935 Andrew Huberman

Dr. Conover, as he will soon tell you, is not a huge proponent of supplements, but he does mention several that he feels are of particular use, including things like coenzyme Q10 and some of the methylated B vitamins, and he explains why he takes that stance. So today's discussion is really for anybody interested in mental health, physical health, and performance.

141.035 - 160.014 Andrew Huberman

And the reason I say that is that even if you aren't considering taking peptides or already taking peptides, peptides and some of these other compounds I've mentioned sit somewhere between doing nothing except diet and exercise which I sort of see as the next step up the ladder in terms of augmenting your health approaches.

160.655 - 177.939 Andrew Huberman

And then of course, there are a number of prescription drugs, including hormone therapies, such as growth hormone therapies, testosterone therapies, and a number of other things that yes, can modify those hormone pathways. They are in fact hormones, but they actually can shut down one's natural production of those hormone pathways.

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