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Dr. Craig Koniver

๐Ÿ‘ค Speaker
906 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

different dosages 250 500 750 000 on up and i just found collectively by watching people how they did 750 milligrams was a sweet spot meaning they'd get the benefits which we can talk about but then they could get through it in an hour or two hours and that was meaningful and then we found that we don't need 10 straight days that's too much that just is crazy we found that five treatments in 10 days again afforded people

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

The ability to have great benefits, which were uniform, probably 95% of people who do a loading test will come back and tell you their brain is getting bigger, they feel more creative, they have an elevated mood, they can sleep less but have more energy, colors look brighter, languaging is easier. I mean, this is all very real.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

The ability to have great benefits, which were uniform, probably 95% of people who do a loading test will come back and tell you their brain is getting bigger, they feel more creative, they have an elevated mood, they can sleep less but have more energy, colors look brighter, languaging is easier. I mean, this is all very real.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

The ability to have great benefits, which were uniform, probably 95% of people who do a loading test will come back and tell you their brain is getting bigger, they feel more creative, they have an elevated mood, they can sleep less but have more energy, colors look brighter, languaging is easier. I mean, this is all very real.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

So I think it affects the nervous system first, just because of the concentration of the mitochondria for every single neuron in the body. The physical components, meaning recovery and helping with physical exercise, those come, but I think they come later. And so we settled on 750 milligrams. We settled on the loading dose.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

So I think it affects the nervous system first, just because of the concentration of the mitochondria for every single neuron in the body. The physical components, meaning recovery and helping with physical exercise, those come, but I think they come later. And so we settled on 750 milligrams. We settled on the loading dose.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

So I think it affects the nervous system first, just because of the concentration of the mitochondria for every single neuron in the body. The physical components, meaning recovery and helping with physical exercise, those come, but I think they come later. And so we settled on 750 milligrams. We settled on the loading dose.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

And then what I noticed is that people were coming back between three and four weeks saying, hey, I don't feel as good as I did after I did that loading dose. And so we started doing a once a month maintenance dose. And that is what we still recommend to today. Some people will do less and some people do more. I have some people who do it once a week, but plenty of people do it once a month.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

And then what I noticed is that people were coming back between three and four weeks saying, hey, I don't feel as good as I did after I did that loading dose. And so we started doing a once a month maintenance dose. And that is what we still recommend to today. Some people will do less and some people do more. I have some people who do it once a week, but plenty of people do it once a month.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

And then what I noticed is that people were coming back between three and four weeks saying, hey, I don't feel as good as I did after I did that loading dose. And so we started doing a once a month maintenance dose. And that is what we still recommend to today. Some people will do less and some people do more. I have some people who do it once a week, but plenty of people do it once a month.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

And then some people do it quarterly. Some people do it whenever they can. On average, once a month seems to work really well for people. Then during the pandemic and realizing this is growing, because again, we train practices kind of in the medicine that we practice. We've trained 300, 350 practices and kind of give them the playbook, so to speak.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

And then some people do it quarterly. Some people do it whenever they can. On average, once a month seems to work really well for people. Then during the pandemic and realizing this is growing, because again, we train practices kind of in the medicine that we practice. We've trained 300, 350 practices and kind of give them the playbook, so to speak.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

And then some people do it quarterly. Some people do it whenever they can. On average, once a month seems to work really well for people. Then during the pandemic and realizing this is growing, because again, we train practices kind of in the medicine that we practice. We've trained 300, 350 practices and kind of give them the playbook, so to speak.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

People weren't coming to the office as much with COVID. So we started doing it subcutaneously. And actually that's worked out really well. We'll do 100 milligrams subcutaneously. Again, five days on, take two days off. You get a little bit of that stomach cramping from the 100 milligram injection. Like you said, can't really be absorbed well orally, not gonna really work.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

People weren't coming to the office as much with COVID. So we started doing it subcutaneously. And actually that's worked out really well. We'll do 100 milligrams subcutaneously. Again, five days on, take two days off. You get a little bit of that stomach cramping from the 100 milligram injection. Like you said, can't really be absorbed well orally, not gonna really work.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

People weren't coming to the office as much with COVID. So we started doing it subcutaneously. And actually that's worked out really well. We'll do 100 milligrams subcutaneously. Again, five days on, take two days off. You get a little bit of that stomach cramping from the 100 milligram injection. Like you said, can't really be absorbed well orally, not gonna really work.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

So you're gonna have to inject it or infuse it. Agreed, there's a price point here. It's going to cost money. But like most things, it's to me, if I had to pick one thing for people, engaging in NAD would be it. Really? Yeah, yeah, I would.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

So you're gonna have to inject it or infuse it. Agreed, there's a price point here. It's going to cost money. But like most things, it's to me, if I had to pick one thing for people, engaging in NAD would be it. Really? Yeah, yeah, I would.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

So you're gonna have to inject it or infuse it. Agreed, there's a price point here. It's going to cost money. But like most things, it's to me, if I had to pick one thing for people, engaging in NAD would be it. Really? Yeah, yeah, I would.

Huberman Lab
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver

Of all the things. I've just been so impressed over the years. Now, peptides are amazing. Not to knock peptides. There's so many peptides, and we'll get there, right? Because you can take this peptide for the nervous system, this peptide for the immune system. But collectively, one agent, one thing, it's NAD has been the most impactful from where I sit working with patients.