Dr. Craig Koniver
๐ค SpeakerAppearances Over Time
Podcast Appearances
So PT-141, what they found is in rats, I think it was, female rats were copulating more when they got this compound. And they're like, oh, cool, and let's try it in humans. And it's led to that. Our trouble with it is a very small or narrow therapeutic window. And if you give too much, you're going to get nauseous pretty quickly. Yeah.
And some people don't like, particularly women, don't like that tanning look.
And some people don't like, particularly women, don't like that tanning look.
And some people don't like, particularly women, don't like that tanning look.
Unnatural is the word.
Unnatural is the word.
Unnatural is the word.
Yeah. And to touch on that is what we found is if we start with, again, a microdose and go slowly with the GLP-1s, The knowledge is virtually unheard of. Not saying it doesn't occur, but it's super rare if you just take your time with it. I think when people have most problems, they're shotgunning the dose, essentially. You're overwhelming your system.
Yeah. And to touch on that is what we found is if we start with, again, a microdose and go slowly with the GLP-1s, The knowledge is virtually unheard of. Not saying it doesn't occur, but it's super rare if you just take your time with it. I think when people have most problems, they're shotgunning the dose, essentially. You're overwhelming your system.
Yeah. And to touch on that is what we found is if we start with, again, a microdose and go slowly with the GLP-1s, The knowledge is virtually unheard of. Not saying it doesn't occur, but it's super rare if you just take your time with it. I think when people have most problems, they're shotgunning the dose, essentially. You're overwhelming your system.
I think it's probably both I think You know, I would say that unfortunately a lot of times when the government acts they overreach, right? Like I do think they probably have good intentions I think there's a there's probably sound reasons to want to have oversight of things that seemingly is the wild wild west right and there's truth to that and Right?
I think it's probably both I think You know, I would say that unfortunately a lot of times when the government acts they overreach, right? Like I do think they probably have good intentions I think there's a there's probably sound reasons to want to have oversight of things that seemingly is the wild wild west right and there's truth to that and Right?
I think it's probably both I think You know, I would say that unfortunately a lot of times when the government acts they overreach, right? Like I do think they probably have good intentions I think there's a there's probably sound reasons to want to have oversight of things that seemingly is the wild wild west right and there's truth to that and Right?
Because peptides came on the scene and people started using them. They're recommended here and there. People could get them from, still can, research companies. And there's not a lot of corralling of understanding, well, what is going on? So I'm sure there's an element to like, hey, let's understand this better. But on that side, I think they went too far, right?
Because peptides came on the scene and people started using them. They're recommended here and there. People could get them from, still can, research companies. And there's not a lot of corralling of understanding, well, what is going on? So I'm sure there's an element to like, hey, let's understand this better. But on that side, I think they went too far, right?
Because peptides came on the scene and people started using them. They're recommended here and there. People could get them from, still can, research companies. And there's not a lot of corralling of understanding, well, what is going on? So I'm sure there's an element to like, hey, let's understand this better. But on that side, I think they went too far, right?
Because I think if you really look at data or if you were really interested in that, there's ways to understand how things work without removing them from the marketplace. So the other side of me is like, just like we're talking about. Ozempic and Mangiorno, semaglutide and terzepatide, are blockbuster drugs.
Because I think if you really look at data or if you were really interested in that, there's ways to understand how things work without removing them from the marketplace. So the other side of me is like, just like we're talking about. Ozempic and Mangiorno, semaglutide and terzepatide, are blockbuster drugs.
Because I think if you really look at data or if you were really interested in that, there's ways to understand how things work without removing them from the marketplace. So the other side of me is like, just like we're talking about. Ozempic and Mangiorno, semaglutide and terzepatide, are blockbuster drugs.
If you're a pharmaceutical company and you see that there's 15 to 20 other peptides which are really working and really working because, again, we've just seen the clinical response over and over and over, It's not a large leap to think, hey, if we're a pharmaceutical company, what if we turn that peptide, which was available to the commoner, for lack of a better term, into a drug? Like Vilisi.