Dr. Darren Candow

So think of anti-catabolic to the bone.

We have not shown in a single study an increased bone mineral density.

So this is really crucial.

We are not saying that creatine and weight training increases bone mineral density, but it certainly decreases bone mineral density loss and really specifically around the hip region, which is crucially important for a lot of older adults because when they fall, if they land on their hip, they could be more susceptible to fracture.

So there's a lot of anti-catabolic effects.

And we've just shown in a long-term clinical trial that improved bone strength.

So picture a pen or pencil.

You can't crack it as much there.

I think weight training is the main driver when it comes to bone.

The more muscle you have from an indirect perspective, there's more muscle pulling on bone.

So that's very beneficial.

Look at gymnasts.

They have

phenomenal bone mineral density and muscle mass there.

So there's a lot of potential there.

It's not overwhelmingly convincing, I think, because bone takes a long time to turn over.

But this is interesting.

The lowest dose ever been shown to be effective is eight grams of monohydrate a day.

Now, as we just talked about, three to five grams is great for muscle, but now you're getting into bone.

What needs to happen is a dosing study.