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Dr. Darren Candow

๐Ÿ‘ค Speaker
1177 total appearances

Appearances Over Time

Podcast Appearances

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

So they had elite rugby players do a crossover design.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

And a crossover design is really powerful.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

That means the group gets both placebo and creatine.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

So it really controls for diet, genetics, hormones, things like that.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

When they took 20 grams a day, it might have been even 25 grams a day for seven days during the creatine supplementation phase, they increased the hormone dihydroxy testosterone or DHT.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

And most people say, oh, I think I've seen commercials about this.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

It's a surrogate of testosterone, but it's been highly linked to hair follicle loss and thinning from a cellular perspective.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

They measured it in the blood, so the correlation, you know, it's just a surrogate.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

But when they went up, I think it went up by about 57%, but it was still within the physiological range.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

And what I mean by that is when you go to your doctor and they measure your blood glucose and it comes back and the doctor says, no, it's within the normal range, cholesterol's in the normal range, even increasing by 57%, I think that was the number.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

It was still within the normal range.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

When they were on placebo, it increased by about 40%.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

So everybody says, whoa, hormone went up?

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

correlation, causation, everybody was freaking out that this hormone went up.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

They did not measure hair follicle loss, thinning, cross-sectional area, no dermatologist was involved, but a lot of people have run with this.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

And to this day, they cite this single study that even didn't look at free testosterone.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

There was no increase.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

So just because DHT went up a little bit and they start at lower, so there was more room to improve, people think it causes baldness.

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

I've assessed easily over a thousand people

FoundMyFitness
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD

Males and females, not a single person has said, hey, whatever you're giving to me, double blind is causing my hair to fall out.