Dr. Darshan Shah
๐ค PersonAppearances Over Time
Podcast Appearances
plasma on top and there's like a little.
plasma on top and there's like a little.
plasma on top and there's like a little.
So the soup is where all of the... In other words, what's in the plasma? Yeah, exactly. What's in the plasma, right? So this is where all your cells are living, and this is what they're exposed to on a day-to-day basis. It's the growth factors, it is cell signaling molecules, it's nutrients, it's a lot of the factors of your immune system live in this soup.
So the soup is where all of the... In other words, what's in the plasma? Yeah, exactly. What's in the plasma, right? So this is where all your cells are living, and this is what they're exposed to on a day-to-day basis. It's the growth factors, it is cell signaling molecules, it's nutrients, it's a lot of the factors of your immune system live in this soup.
So the soup is where all of the... In other words, what's in the plasma? Yeah, exactly. What's in the plasma, right? So this is where all your cells are living, and this is what they're exposed to on a day-to-day basis. It's the growth factors, it is cell signaling molecules, it's nutrients, it's a lot of the factors of your immune system live in this soup.
So it's basically where all the signaling in your body kind of lives inside of this plasma. And what's good about it is that it carries these signals throughout your entire body. So if you have something going on in your gut, your brain can hear about it. If you have something going on in your heart, your gut hears about it.
So it's basically where all the signaling in your body kind of lives inside of this plasma. And what's good about it is that it carries these signals throughout your entire body. So if you have something going on in your gut, your brain can hear about it. If you have something going on in your heart, your gut hears about it.
So it's basically where all the signaling in your body kind of lives inside of this plasma. And what's good about it is that it carries these signals throughout your entire body. So if you have something going on in your gut, your brain can hear about it. If you have something going on in your heart, your gut hears about it.
Exactly. One of the functions it has is being a communication superhighway for your entire body.
Exactly. One of the functions it has is being a communication superhighway for your entire body.
Exactly. One of the functions it has is being a communication superhighway for your entire body.
Right, right, right, exactly. So let's take it back a little bit more also to the convoys with the parabiosis experiment. I think that's interesting to talk about where they hook up a young mouse to an old mouse. And they found that the old mouse got younger and the young mouse got older.
Right, right, right, exactly. So let's take it back a little bit more also to the convoys with the parabiosis experiment. I think that's interesting to talk about where they hook up a young mouse to an old mouse. And they found that the old mouse got younger and the young mouse got older.
Right, right, right, exactly. So let's take it back a little bit more also to the convoys with the parabiosis experiment. I think that's interesting to talk about where they hook up a young mouse to an old mouse. And they found that the old mouse got younger and the young mouse got older.
And so for a decade, people were looking for like, what is the substance in the young mouse that makes the old mouse younger? And so they did all these studies and substances like GDF11, TNF, and nothing really panned out. And then 10 years later, There's a story. I think it's a true story because I hear it all the time.
And so for a decade, people were looking for like, what is the substance in the young mouse that makes the old mouse younger? And so they did all these studies and substances like GDF11, TNF, and nothing really panned out. And then 10 years later, There's a story. I think it's a true story because I hear it all the time.
And so for a decade, people were looking for like, what is the substance in the young mouse that makes the old mouse younger? And so they did all these studies and substances like GDF11, TNF, and nothing really panned out. And then 10 years later, There's a story. I think it's a true story because I hear it all the time.
Someone at a conference went up to ask a question to the scientist doing all the research on this, and they kind of knocked on the microphone and they said, you know, I think you guys are looking at the wrong mouse. It's not what's in the old mouse. It's not what's in the young mouse making the old mouse younger. It's the opposite. It's what you're taking out of the old mouse.
Someone at a conference went up to ask a question to the scientist doing all the research on this, and they kind of knocked on the microphone and they said, you know, I think you guys are looking at the wrong mouse. It's not what's in the old mouse. It's not what's in the young mouse making the old mouse younger. It's the opposite. It's what you're taking out of the old mouse.