Dr. David Fajgenbaum
๐ค SpeakerAppearances Over Time
Podcast Appearances
And that's when I told them that I'm going to dedicate the rest of my life, however long that is, trying to find a treatment for Castleman disease.
And I didn't know what that would be.
And frankly, I didn't have a billion dollars in 10 years to create a new drug, which is about how much time and money it costs if you want to make a brand new drug.
So I didn't have the money and I didn't have the time, but I had a really simple and important realization, and that was those seven chemotherapies that I kept getting that kept sort of barely saving my life, none of them were made for Castleman disease.
They were all made for cancer of the lymph nodes for lymphoma.
but they were saving my life from Castleman.
So I was like, well, wait a minute.
You're telling me there's no more drugs for Castleman disease, but you just used seven drugs for lymphoma and those just saved my life.
So like, what if there's an eighth drug for lymphoma?
What if there's a ninth drug for something else that could work for Castleman's?
And my doctors were sort of like, well, but there's nothing else that we know of.
And I'm like, yeah, but have we tried all 4,000 drugs for Castleman disease?
And so that became my just total like locked in focus.
It was like, I can't develop a new drug from scratch.
I want to get married to Caitlin, have a family.
I want to develop drugs and treat patients.
I got to find a drug that already exists for something else.
And then I got to try it on me.
And that became just my total focus.
Where do you start?