Dr. David Fajgenbaum
๐ค SpeakerAppearances Over Time
Podcast Appearances
We want to do it more like this.
You can run experiments and see like, what's the best way to get the best results?
And if it's a 17 hour turnaround time, you can just keep doing it.
I think so.
A part of it could be.
So when we score every drug against every disease,
you now, in that database, you now would have a bunch of drugs for diseases that score poorly or that are middle level.
And so there's parts of it that maybe would be not that helpful, but the things at the top, absolutely.
The things at the top very much can be, so, you know, at the very top for, let's say for a horrible disease, let's say like ALS,
there's two drugs that are FDA approved for ALS.
They don't work very well, but there are two drugs that are FDA approved.
That's got to be at the very top of the list.
And then right below those two FDA approved drugs, there are some drugs that are sometimes tried where there's early data that should be next in the list.
And then you should get into like these sort of AI predictions of like, well, what's AI telling us?
But what I wouldn't want is for people to sort of
skip the things at the top where there's like good data and just go to like what AI is predicting because for us like at every cure when we make these predictions we look at the things at the very top but we don't automatically say whatever score is number one we're going to give to patients it's like whatever score is number one we're going to look really deeply into it we're going to study in the lab we're going to do clinical trials and we're going to figure out is it the right thing for patients but not necessarily we don't trust fully in AI is basically what I'm saying it's like AI for us is a great starting point but there's still more work to be done
Yeah, so there's one of our programs.
So we've got six active programs at EveryCure, so different drugs that we're repurposing for diseases.
And one of them is around the numbing medicine lidocaine.
So when you go to the dentist, you get an injection of lidocaine and the role that it can play in preventing recurrence of breast cancer.