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Dr. David Sinclair

๐Ÿ‘ค Person
348 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Right.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Well, so longevity is the more academic way we describe what we research.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Anti-aging is kind of the same thing, but it's got a bad rap because it's been used by a whole bunch of people that don't know what they're talking about.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

So I really don't like that term anti-aging.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

But aging as a disease and longevity are perfectly valid ways to talk about this subject.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

So let's talk about aging as a disease.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

When I started my research, disease here at Harvard Medical School, it was considered if there's something that's wrong with you,

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

and it's a rare thing, has to be less than 50% of the population, that's definitely a disease.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

And then people work their whole lives to try and cure that condition.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

And so I looked up what's the definition of aging, and it says, well, it's a deterioration in health and sickness, and you can die from it, typically you do.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

So I'm thinking that sounds pretty much like a disease, but the caveat is that if more than half the population gets this condition, aging,

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

It's put in a different bucket, which is, first of all, that's outrageous because it's just a totally arbitrary cutoff.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

But think about this, that we're ignoring the major cause of all these diseases.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Aging is 80% to 90% the cause of heart disease, Alzheimer's.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

If we didn't get old and our bodies stayed youthful, we would not get those diseases.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

And actually, what we're showing in my libels, if you turn the clock back in tissues, those diseases go away.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

So aging is the problem.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

And instead, through most of the last 200 years, we've been sticking Band-Aids on diseases that have already occurred because of aging.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

And then it's too late.

Huberman Lab
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

So there are a couple of things.

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