Dr. David Sinclair

Free, like I want to jump.

So let's...

hope, pray, wish that these technologies that I'm talking about today work.

Because that could be what it feels like to be rejuvenated when you're 80.

Part of it came out of research in my lab, but of course many others I need to give credit to.

But in my lab specifically, what we worked on initially when I started, we studied yeast cells, little microscopic cells that, as everyone knows, we use to make beer and bread and champagne.

These yeast cells live about 10 days and then they die.

And we used yeast as a model for aging.

And what we discovered with yeast cells, which turns out to be true in our bodies, is that adversity, as long as it's not killing these cells, is good for you.

It's called hormesis.

It's the technical term for what doesn't kill you makes you stronger and live longer.

Adversity mode is what we're aiming for.

The opposite is abundance mode, which is what modern life is all about.

Popcorn, movies, wheels on your suitcase, sitting down all day.

We're in an abundance world.

So adversity is something we don't often feel.

We have to work at it.

Fasting is adversity.

Exercise is adversity.

Cold plunges, saunas, adversity.