Dr. David Sinclair

It used to come from sperm?

Well, that's how it was discovered.

It was crystallized by, I believe, Anthony von Leeuwenhoek, one of the first microscopists and microbiologists.

Spermidine, the reason that I take it is that it extends the lifespan of every animal that it's been given to, from worms to mice.

And it's a very safe molecule.

So I always weigh up the downsides versus the upsides.

And if there's no downsides and I can afford it, which I work really hard so I can afford it and I prioritize my health, then I take it.

And if you're wondering how it works, it seems to stimulate autophagy, recycling of proteins.

It helps with the fasting.

But I also have some evidence that it delays the epigenetic information loss.

So it's slowing down the scratching of the record.

Spermidine.

All right.

So I'm also keen on glycine.

Glycine is a very safe substance.

It's an amino acid, one of the 20 amino acids that makes proteins.

And I actually did a PhD on glycine.

I was one of the first people to, perhaps the first person to clone genes that process glycine.

So I know it well.

For some reason, when you give animals and, for instance, mice, grams of glycine, so I take about five grams of glycine most days, they live longer.