Dr. David Sinclair

If we didn't get old and our bodies stayed youthful, we would not get those diseases.

And actually, what we're showing in my libels, if you turn the clock back in tissues, those diseases go away.

So aging is the problem.

And instead, through most of the last 200 years, we've been sticking Band-Aids on diseases that have already occurred because of aging.

And then it's too late.

So there are a couple of things.

One is we want to slow aging down so we don't get those diseases.

And when they do occur, don't just stick a Band-Aid on, reverse the age of the body, and then the diseases will go away.

Fortunately, during the 2000s, we settled on eight or nine major causes of aging.

These eight or nine causes, at least for the first time, allowed us to come around and talk together.

We put them on a pizza, so everyone got equal slices.

But I think that there's one slice of the pizza that is way larger than the others.

And we can get to that, but that's the information in the cell that we call the epigenome.

Yeah.

So in science, what I like to do, I'm a reductionist, is to boil it down.

And I actually ended up boiling aging down to an equation.

which is the loss of information due to entropy.

It's a hard thing to overcome, the second law of thermodynamics, that's fair.

But this equation really represents the fact that I think aging is a loss of information in the same way that when you Xerox something a thousand times, you'll lose that information, or you try to copy a cassette tape, or even if you send information across the internet, some of it will get lost.

That's what I think is aging.