Dr. David Sinclair

And there are two types of information in the body.

There is the genetic information, which is digital, A-T-C-G, the chemical letters of DNA.

But there's this other part of the information in the body that's just as important,

essential in fact and that's the systems that control which genes are switched on and off in what cell at what time in response to what we eat etc and it turns out that 80 of our future longevity and health is controlled by this second part the epigenetic information the control systems

I liken the DNA to the music that's on a DVD or a compact disc for the younger people.

We used to use these things.

I recall.

Yeah.

And then the epigenome is the reader that says, okay, in this cell, we need to play that set of songs.

And in this other cell, we have to play a different set of songs.

But over time, aging is the equivalent of scratching.

the CD and the DVD so that you're not playing the right songs.

And cells, when they don't hear the right songs, they get messed up and they don't function well.

And that is what I'm saying is the main driver of aging.

And these other hallmarks are largely manifestations of that process.

What are the scratches that you're referring to?

So DNA is six foot long.

So if you join your chromosomes together, you get about six foot per cell.

So there's enough to go to the moon and back eight times in your body.

And it has to be wrapped up to exist inside us.