Dr. David Sinclair

Like quitting smoking cold turkey, it's easier to chew gum and stick the patch on.

Because your body has to get used to all sorts of habits.

And it's social.

It's physical.

Putting stuff in your mouth.

Chewing.

Not just the low blood sugar levels.

And your brain will fight it.

Your limbic system is going to go, hey, do it, do it, do it.

And you're going to have to fight it.

But once you get through it, you'll be better.

But you do it in stages.

Don't go cold turkey.

Because everyone knows...

It's a fact that if you try to do a strict diet right out of the gates, you'll almost always fail.

All right.

Well, disclaimer is that I don't recommend anything, but I talk about what I do.

So a bit of scientific background, these sirtuin genes that we discovered first in yeast cells when I was at MIT and then in animals as I moved to Harvard in the 2000s.

And one of my first postdocs, actually literally my first postdoc, Chaim Cohen, published a great paper and found that turning on the sirtuin 6 gene, remember the 7, number 6 gene is very potent.

It extended the lifespan dramatically of mice that he engineered.