Dr. Diego Bohórquez
👤 SpeakerAppearances Over Time
Podcast Appearances
I think that it goes from like two to seven fold.
The likelihood that they become, they will develop alcoholism.
Really?
Yes.
Because now the way that they describe it is like, well, you know, either before I didn't like wine.
And then now I, you know, after a few months of a surgery, I'll have one glass of wine.
And then all of a sudden I found myself going to two, three, four.
And then they will become either more sensitive.
It's still not known the entire biology, but they will become either not only more sensitive, but more attracted to that type of stimulus.
Yes, that's a complimentary question.
And in fact, when I got into studying in this field 15 years ago, the study among scientists in this area, glucagon-like peptide was already very popular in the study.
In fact, in this area, people were very focused on the study of this peptide.
And they were very focused on the study of this peptide because it was one of the most potent stimulators of insulin release in the pancreas.
After gastric bypass surgery, it will actually increase its amount in circulating levels.
And there were already some studies suggesting that the effect of this glucagon-like peptide, it was actually not through the circulation, but more in a localized action onto nerve fibers.
especially of the vagus nerve.
So there was already like some ongoing discussion about this.
And certainly some of these enteroendocrine cells, these neuroendocrine cells, particularly at least in animals, I think it's more distal and in the digestive tract, that they do release this glucagon-like peptide.
One, in response to primarily like
all of the macronutrients, but primarily sugar.