Dr. Diego Bohórquez

Today we just talked about the esophagus, right?

Like the esophagus, I think that it's still, there is a little bit of work.

Perhaps I think that Steve Lieberlitz has worked in that area, another great neuroscientist doing some very fine detailed work in sensory biology.

in the esophagus, there is quite a bit of lack of precise biology in how it is that the esophagus, the specific cells of the esophagus are innervated or like making sense of the environment.

Same thing for the stomach and how it is that ultimately each one of those regions are feeding into different regions of the brain.

Even then, how each one of these valves

I'm fascinated by each one of the valves that we talked early on, like the gastroesophageal sphincter or the pylorus or the ileocecal junction.

to the brain.

That's correct.

And here's something that since we're getting into the future of this area, and while there is not direct published evidence yet, I think that is going to be a fun area.

So the gut as the brain also generates these electrical patterns.

Those electrical patterns change depending on fasting versus feeding and circadian rhythms.

probably can realize jet lag.

The gut is asking you for a burger at 3 a.m.

and your brain is telling the gut, you know, can you please go to sleep, right?

So these electrical patterns, these electrical waves that are going into, that are being propagated by the gastrointestinal tract, there are like several different cells, like the enteric neurons are coordinating these cells

there are also these interstitial cells of Cajal

So Santiago Ramon y Cajal.

The greatest neurobiologist of all time.

That's right.