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Dr. Diego Bohórquez

👤 Speaker
956 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

It's like Google Maps.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

Everything connects to everything.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

The first hubs of sensory integration are in the brainstem.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

And for instance, the nucleus tractus solitarius is in a specific region we

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

in the brain.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

The caudal is one area.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

And NTS, for those that don't know, is involved in regulating hunger and appetite.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

That's correct.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

Other functions, perhaps, but like, for instance, that seems to be an area of sensory integration for nutrients.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

Yes.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

And there has been some elegant work from several different neuroscientists in this area, like tracking the circuitry.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

From there on to many other different areas.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

The hypothalamus, for instance, very basic behavioral functions.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

And the striatum, where there is dopamine release, and then there is this pleasurable sensation and reward.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

There are several other areas in there that are involved in this sensory integration.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

There is quite a bit of work still to be done from specifically from the neuropods.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

There is like some evidence that they are connecting directly to or there are

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

If you put two papers together, it's obvious that they are connecting to like some of these areas of dopamine release, basal ganglia in the brain.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

And that's why they are causing this reinforcing effect like in the lateral hypothalamus and other areas.

Huberman Lab
Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

I do think that ultimately there is quite a bit of a gap in like different regions of the digestive tract.