Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
You know, it was like, I don't have a two or three day hiatus here that I can just get sick.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
But finally I said, well, the data here are really compelling.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
But that's just, we don't, the shingles vaccine is an example of revving up the immune system in older adults.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
And that's what we're, you know, in the future, we're going to be using vaccines just to bring the immune system up at a higher level to maintain its integrity.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
And we're going to use anti-inflammatory drugs.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
So these drugs like Ozempic and Moonjaro, they're real actions.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
It's not just about weight loss or helping diabetes.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
It's about inflammation.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
They are potent blockers of brain inflammation, testing now in Alzheimer's, in big trials, and also body-wide inflammation, which is critical in cancer and in heart disease.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
So we're going to be using these drugs in the future in pill form.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
To block inflammation.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
And if those trials are coming out in early next year for Alzheimer's work, for these, you know, ozempic-like drugs, that's going to be one of the biggest changes in the history of medicine.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
We've not had a really potent and safe anti-inflammatory drug, especially that gets its effects through the brain.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
You know, I speculated that in super ages because that's where it looks like we're headed.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
And remember, we're still in the early days.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
We have these two hormone, gut hormone memetics, basically, that look like the hormones that we have naturally in our body.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
There's another 15 more that have been discovered.
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Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
that are gonna be made into pills like these are, and all kinds of combinations.
Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
And what we've learned is that the gut speaks to the brain and the immune system through these hormones.
Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan
So, you know, it used to be thought that a way to a man's heart was through his gut.