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Dr. Eric Topol

๐Ÿ‘ค Speaker
676 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

I mean, that's kind of a new frontier that we don't know enough about.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

So whether we can manipulate the bacteria in our gut or their metabolites, the stuff that they make while they're in our gut, residents in our body,

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

We don't know how to do that yet.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

There's a lot of work being done.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

We only have one disease that they can help with, that manipulation with prebiotics and basically changing our constituents.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

And that's this pseudomembranous colitis bacteria caused by Clostridium difficile.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

But other than that, we are in the dark.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

And so we don't know.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

I do think that's going to be another.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

We were talking, Katie, earlier about the gut hormones talking to the brain.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

But the gut microbiome is another way that is central to our immune system.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

So we're learning how to engineer that.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

I mean, you know, Jennifer Doudna is trying to do editing of our gut.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

Yeah, CRISPR to prevent asthma.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

Wouldn't that be something?

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

But our gut microbiome and the things it makes are critical to our immune system and inflammation.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

We just don't know how to control it yet.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

And so the things that are out there now that, you know, call it prebiotics and antibiotics, we don't know how they work and they don't have any data evidence that they're really doing anything yet.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

Well, plant-based foods, fruits and vegetables, nuts, legumes, these are things, fiber.

Ground Truths
Katie Couric and Eric Topol: On the State of US Life Science and Extending Healthspan

These are all anti-inflammatory.