Dr. Eric Verdin
๐ค SpeakerAppearances Over Time
Podcast Appearances
And the last one, I mean, that I, you know, physical activity exercise is certainly a very strong way to activate mitochondrial function in your muscle. And we know, you know, your muscle mass is a very strong predictor of your life expectancy. So
Anything that benefits your muscle, having strong mitochondria, bulk, frankly, also of your muscle will lead to protective effect on your brain and other organs as well. So obviously, you know, whenever we're talking about anything related to aging, the reductionist approach works for a while to try to simplify the models.
Anything that benefits your muscle, having strong mitochondria, bulk, frankly, also of your muscle will lead to protective effect on your brain and other organs as well. So obviously, you know, whenever we're talking about anything related to aging, the reductionist approach works for a while to try to simplify the models.
Anything that benefits your muscle, having strong mitochondria, bulk, frankly, also of your muscle will lead to protective effect on your brain and other organs as well. So obviously, you know, whenever we're talking about anything related to aging, the reductionist approach works for a while to try to simplify the models.
But once you start thinking about anything, it's connected to everything else.
But once you start thinking about anything, it's connected to everything else.
But once you start thinking about anything, it's connected to everything else.
Yeah, happy to talk about this because, frankly, once you are involved in the research and you see some of the stuff that's being sold, sometimes I shake my head in disbelief. But that being said, there's like in any story, there's always an element of truth to the whole NAD story. So just a word about NAD is a molecule that allows you to shuttle energy between different parts of the cell.
Yeah, happy to talk about this because, frankly, once you are involved in the research and you see some of the stuff that's being sold, sometimes I shake my head in disbelief. But that being said, there's like in any story, there's always an element of truth to the whole NAD story. So just a word about NAD is a molecule that allows you to shuttle energy between different parts of the cell.
Yeah, happy to talk about this because, frankly, once you are involved in the research and you see some of the stuff that's being sold, sometimes I shake my head in disbelief. But that being said, there's like in any story, there's always an element of truth to the whole NAD story. So just a word about NAD is a molecule that allows you to shuttle energy between different parts of the cell.
So this is a purely intracellular molecule. So this is not something that lives in the blood. And so this will be important because there's a whole fad right now of intravenous NAD, which frankly does not make any sense to me biologically. So NAD is an intracellular, and it doesn't cross from the blood into your cells. So it is an intracellular metabolite. Why is it important?
So this is a purely intracellular molecule. So this is not something that lives in the blood. And so this will be important because there's a whole fad right now of intravenous NAD, which frankly does not make any sense to me biologically. So NAD is an intracellular, and it doesn't cross from the blood into your cells. So it is an intracellular metabolite. Why is it important?
So this is a purely intracellular molecule. So this is not something that lives in the blood. And so this will be important because there's a whole fad right now of intravenous NAD, which frankly does not make any sense to me biologically. So NAD is an intracellular, and it doesn't cross from the blood into your cells. So it is an intracellular metabolite. Why is it important?
Because it allows you to shuttle energy between different parts of the cells, from the mitochondria to the cytoplasm and so on, or from different molecules within the cell, more correctly. So it's also known that NAD levels decrease during aging, and that's really well established in humans and in animal models.
Because it allows you to shuttle energy between different parts of the cells, from the mitochondria to the cytoplasm and so on, or from different molecules within the cell, more correctly. So it's also known that NAD levels decrease during aging, and that's really well established in humans and in animal models.
Because it allows you to shuttle energy between different parts of the cells, from the mitochondria to the cytoplasm and so on, or from different molecules within the cell, more correctly. So it's also known that NAD levels decrease during aging, and that's really well established in humans and in animal models.
Out of this came the idea that maybe this is one of the reasons why we have this global energy deficit as we age. Maybe we're not able to manage. So when I think about NAD, you think about Brinkman, you know, the trucks that carry
Out of this came the idea that maybe this is one of the reasons why we have this global energy deficit as we age. Maybe we're not able to manage. So when I think about NAD, you think about Brinkman, you know, the trucks that carry
Out of this came the idea that maybe this is one of the reasons why we have this global energy deficit as we age. Maybe we're not able to manage. So when I think about NAD, you think about Brinkman, you know, the trucks that carry
So think about if they all went on strike, all of a sudden, you know, the energy of the economy, which is money, would be stuck in the supermarket and nothing moves anymore. So this is the same thing. So I think about them as the fund carriers. So out of this came the idea, maybe we can just reestablish NAD levels. And so people will see a benefit. Yeah.