Dr. Eric Verdin
๐ค SpeakerAppearances Over Time
Podcast Appearances
So think about if they all went on strike, all of a sudden, you know, the energy of the economy, which is money, would be stuck in the supermarket and nothing moves anymore. So this is the same thing. So I think about them as the fund carriers. So out of this came the idea, maybe we can just reestablish NAD levels. And so people will see a benefit. Yeah.
So think about if they all went on strike, all of a sudden, you know, the energy of the economy, which is money, would be stuck in the supermarket and nothing moves anymore. So this is the same thing. So I think about them as the fund carriers. So out of this came the idea, maybe we can just reestablish NAD levels. And so people will see a benefit. Yeah.
And in animal models, you can do this using what we call NAD precursors. And there are two of them that you're familiar with, nicotinamide riboside, NR, or nicotinamide mononucleotide, NMN. And both of them essentially do almost the same thing. Some colleagues will argue vociferously on whether one is superior to the other. At the end, they both reestablish NAD levels.
And in animal models, you can do this using what we call NAD precursors. And there are two of them that you're familiar with, nicotinamide riboside, NR, or nicotinamide mononucleotide, NMN. And both of them essentially do almost the same thing. Some colleagues will argue vociferously on whether one is superior to the other. At the end, they both reestablish NAD levels.
And in animal models, you can do this using what we call NAD precursors. And there are two of them that you're familiar with, nicotinamide riboside, NR, or nicotinamide mononucleotide, NMN. And both of them essentially do almost the same thing. Some colleagues will argue vociferously on whether one is superior to the other. At the end, they both reestablish NAD levels.
They might have additional signaling properties in addition to this. And in animal models, they do remarkable things. So we've published... We and many other people in the field have published a number of papers showing that NAD supplementation in older animals really alleviates some of the effects of aging.
They might have additional signaling properties in addition to this. And in animal models, they do remarkable things. So we've published... We and many other people in the field have published a number of papers showing that NAD supplementation in older animals really alleviates some of the effects of aging.
They might have additional signaling properties in addition to this. And in animal models, they do remarkable things. So we've published... We and many other people in the field have published a number of papers showing that NAD supplementation in older animals really alleviates some of the effects of aging.
It does not increase lifespan, I should say, but it certainly alleviates many of the disease complications and so on. So out of this came the interest, well, maybe we should bring this to humans. And a number of companies are selling NR and NMN. One significant issue is that the amounts that are being sold as supplements are much lower by a factor 10 of what we used in the laboratory setting.
It does not increase lifespan, I should say, but it certainly alleviates many of the disease complications and so on. So out of this came the interest, well, maybe we should bring this to humans. And a number of companies are selling NR and NMN. One significant issue is that the amounts that are being sold as supplements are much lower by a factor 10 of what we used in the laboratory setting.
It does not increase lifespan, I should say, but it certainly alleviates many of the disease complications and so on. So out of this came the interest, well, maybe we should bring this to humans. And a number of companies are selling NR and NMN. One significant issue is that the amounts that are being sold as supplements are much lower by a factor 10 of what we used in the laboratory setting.
Exactly.
Exactly.
Exactly.
We used two to three grams.
We used two to three grams.
We used two to three grams.
Exactly. Wow. Of the precursors. Yes. We used a lot more. And those of us who take NMN or NR typically take a lot more than the 200 milligrams a day.
Exactly. Wow. Of the precursors. Yes. We used a lot more. And those of us who take NMN or NR typically take a lot more than the 200 milligrams a day.
Exactly. Wow. Of the precursors. Yes. We used a lot more. And those of us who take NMN or NR typically take a lot more than the 200 milligrams a day.