Dr. Glen Jeffery

Overall, statistically, we saw less of an effect.

Some people, my youngest son responded very, very strongly.

And at the time, I think he was about...

I think he was about 25.

So you have to look at a population level to get that.

But okay, look, this all makes sense.

Mitochondrial theory of aging means that we should have more room to improve mitochondria in the elderly than the young.

But we all age at different rates.

One of the biggest problems about doing experiments on humans as opposed to mice is we all do radically different things.

Some take exercise, some have very good diets, some have poor diets.

And mice sitting in our animal house eating the same food, they're very, very similar to one another, everything is the same.

So we have to accept that noise.

But generally, when your mitochondria are in a poor state, which is consistent with ageing,

Yes, we've got more room to lift them up and improve their function.

Very clear.

Again, same in flies, mice, and humans.

Your biggest effect is always in the morning.

And it's always generally just before perceived sunrise up until about 11 o'clock.

So, and it's very, very clear.

But let's look at the backdrop to this.