Dr. Jeff Bland

So it has a specificity, but it's not the memory effect that you have with the adaptive immune system and antibodies. But I think that what we recognize, and this is an important new aha, is that you can fairly quickly train the innate immune system to be more resilient. It doesn't take months. And how do you do that? Here is where the polyphenols play a principal role.

So it has a specificity, but it's not the memory effect that you have with the adaptive immune system and antibodies. But I think that what we recognize, and this is an important new aha, is that you can fairly quickly train the innate immune system to be more resilient. It doesn't take months. And how do you do that? Here is where the polyphenols play a principal role.

So it has a specificity, but it's not the memory effect that you have with the adaptive immune system and antibodies. But I think that what we recognize, and this is an important new aha, is that you can fairly quickly train the innate immune system to be more resilient. It doesn't take months. And how do you do that? Here is where the polyphenols play a principal role.

This may be, as you said earlier, this list of nutrients that have only gotten a page or two publication in nutrition textbooks because we weren't considered to be essential nutrients, this whole flavonoid family of compounds. Now we're seeing they play principal roles in priming the innate immune system and regulating the genes that are associated with immune defense. This is all new discoveries.

This may be, as you said earlier, this list of nutrients that have only gotten a page or two publication in nutrition textbooks because we weren't considered to be essential nutrients, this whole flavonoid family of compounds. Now we're seeing they play principal roles in priming the innate immune system and regulating the genes that are associated with immune defense. This is all new discoveries.

This may be, as you said earlier, this list of nutrients that have only gotten a page or two publication in nutrition textbooks because we weren't considered to be essential nutrients, this whole flavonoid family of compounds. Now we're seeing they play principal roles in priming the innate immune system and regulating the genes that are associated with immune defense. This is all new discoveries.

I'm talking about the last five years. So this is like aha stuff. that then makes diets become ever more important for how we therapeutically modulate our immune systems.

I'm talking about the last five years. So this is like aha stuff. that then makes diets become ever more important for how we therapeutically modulate our immune systems.

I'm talking about the last five years. So this is like aha stuff. that then makes diets become ever more important for how we therapeutically modulate our immune systems.

Yes, the so-called immunosenescence that you were talking about, inflammation. Yeah. And so now we're starting to recognize that when you get this secretory phenotype of inflammation, because the body has started to collect injury to immune cells and other cells, it gets locked into the state of being constantly, that's where the immune system is aged more than your years of birthdays.

Yes, the so-called immunosenescence that you were talking about, inflammation. Yeah. And so now we're starting to recognize that when you get this secretory phenotype of inflammation, because the body has started to collect injury to immune cells and other cells, it gets locked into the state of being constantly, that's where the immune system is aged more than your years of birthdays.

Yes, the so-called immunosenescence that you were talking about, inflammation. Yeah. And so now we're starting to recognize that when you get this secretory phenotype of inflammation, because the body has started to collect injury to immune cells and other cells, it gets locked into the state of being constantly, that's where the immune system is aged more than your years of birthdays.

And you have an accelerated series of aging that can appear as a brain dysfunction, as a cardiac dysfunction, as diabetes. It can present itself. And by the way, We now recognize that this new class of drugs that we call GLP-1 agonists that are being used for diabetes and for obesity, those affect the immune system through the adipocyte, the fat cells.

And you have an accelerated series of aging that can appear as a brain dysfunction, as a cardiac dysfunction, as diabetes. It can present itself. And by the way, We now recognize that this new class of drugs that we call GLP-1 agonists that are being used for diabetes and for obesity, those affect the immune system through the adipocyte, the fat cells.

And you have an accelerated series of aging that can appear as a brain dysfunction, as a cardiac dysfunction, as diabetes. It can present itself. And by the way, We now recognize that this new class of drugs that we call GLP-1 agonists that are being used for diabetes and for obesity, those affect the immune system through the adipocyte, the fat cells.

So now we're starting to learn that these are all interconnected into another system, which is the gut connected to the fat cell, connected to the brain, connected to the immune system. And so when we're giving GLP-1 agonist drugs, we're also having a therapeutic influence on that system as well.

So now we're starting to learn that these are all interconnected into another system, which is the gut connected to the fat cell, connected to the brain, connected to the immune system. And so when we're giving GLP-1 agonist drugs, we're also having a therapeutic influence on that system as well.

So now we're starting to learn that these are all interconnected into another system, which is the gut connected to the fat cell, connected to the brain, connected to the immune system. And so when we're giving GLP-1 agonist drugs, we're also having a therapeutic influence on that system as well.

Exactly right.

Exactly right.