Dr. Jocelyn Wittstein

And there is some data that suggests that women with surgical menopause maybe are more at risk for sarcopenia as compared to just regular menopause.

Obviously, a more extreme version is you're having so much weakness that you... You're frail.

You're frail.

I mean, like grip strength less than 17 kilograms or something like that for women.

But in general, obviously everything is on a continuum from a large amount of muscle mass to less and weakness.

But there's some data suggests that surgical menopause would put people more at risk for having some loss of muscle mass than...

Yeah, or more at risk for like completing a survey that indicates your strength and muscle function being more at risk for sarcopenia than natural menopause.

So I think we need more information about there are basic science things that make sense in mice models.

I think maybe we'll learn more going forward about actual, you know, what actually happens to muscle mass with some of the more

you know, modern day utilizations.

But those are kind of the components.

Why do you say that?

For multiple reasons.

So the most, one of the largest impacts lifelong of women's

estrogen withdrawal is osteoporosis which largely affects women and is a silent condition so it's easy to overlook it until so late in life that you have a hip fracture or you know a vertebral compression fracture and then who are you seeing at that point usually a male surgeon yeah

And at that point, you know, yes, you know, for instance, where I work, we have a fracture, a fragility clinic that we send people to after a hip fracture, vertebral fracture.

And we, you know, many of these people haven't been tested for the bone density or haven't ever had like a Zolendronate infusion or something like that.

And we're getting them down that path, but it's so late.

And so I think there's this weird thing that happens where women are obviously receiving

a lot of lifelong healthcare through their women's health providers.