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Dr. John Kruse

๐Ÿ‘ค Speaker
915 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And there's a tiny bit of data, but part of it overall is that we talked earlier about global rates of addiction to any substance. That we have fairly good data on because the CDC tracks it. But in terms of very specifically, who gets addicted to Adderall? Who gets addicted to Ritalin?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And there's a tiny bit of data, but part of it overall is that we talked earlier about global rates of addiction to any substance. That we have fairly good data on because the CDC tracks it. But in terms of very specifically, who gets addicted to Adderall? Who gets addicted to Ritalin?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And there's a tiny bit of data, but part of it overall is that we talked earlier about global rates of addiction to any substance. That we have fairly good data on because the CDC tracks it. But in terms of very specifically, who gets addicted to Adderall? Who gets addicted to Ritalin?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

There's so little data and most people just sort the same numbers that, oh, maybe 2% to 3% of kids run into trouble and it's not common and that's it. Or they study a much broader question, and that's the issue of misuse combined with abuse.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

There's so little data and most people just sort the same numbers that, oh, maybe 2% to 3% of kids run into trouble and it's not common and that's it. Or they study a much broader question, and that's the issue of misuse combined with abuse.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

There's so little data and most people just sort the same numbers that, oh, maybe 2% to 3% of kids run into trouble and it's not common and that's it. Or they study a much broader question, and that's the issue of misuse combined with abuse.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And misuse, by the research definitions, means anyone who didn't use their drug exactly as prescribed, which means if you're taking a short-acting Ritalin and it says take it one every six hours apart during the day, and you acknowledge taking it on one day, eight hours difference, you're classified as a misuser by those studies.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And misuse, by the research definitions, means anyone who didn't use their drug exactly as prescribed, which means if you're taking a short-acting Ritalin and it says take it one every six hours apart during the day, and you acknowledge taking it on one day, eight hours difference, you're classified as a misuser by those studies.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And misuse, by the research definitions, means anyone who didn't use their drug exactly as prescribed, which means if you're taking a short-acting Ritalin and it says take it one every six hours apart during the day, and you acknowledge taking it on one day, eight hours difference, you're classified as a misuser by those studies.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

I mean, I'm being maybe a little ridiculous because most of the exceptions aren't that narrow. But there's a big blurring in the research, particularly coming from the people who are worried about addiction. I mean, we should be worried about addiction, but we shouldn't be overreacting or creating, pretending it's a problem among those where that, I would say, is not addiction. That's not abuse.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

I mean, I'm being maybe a little ridiculous because most of the exceptions aren't that narrow. But there's a big blurring in the research, particularly coming from the people who are worried about addiction. I mean, we should be worried about addiction, but we shouldn't be overreacting or creating, pretending it's a problem among those where that, I would say, is not addiction. That's not abuse.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

I mean, I'm being maybe a little ridiculous because most of the exceptions aren't that narrow. But there's a big blurring in the research, particularly coming from the people who are worried about addiction. I mean, we should be worried about addiction, but we shouldn't be overreacting or creating, pretending it's a problem among those where that, I would say, is not addiction. That's not abuse.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

That's not using it as directed. But people with ADHD, by their very nature, are not going to use things as directed, either because they forgot or weren't organized enough to get it on time, or forgot what you said in the office, even though you wrote it down because they lost a sheet of paper it's written down on. So getting back to patient's experience of it.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

That's not using it as directed. But people with ADHD, by their very nature, are not going to use things as directed, either because they forgot or weren't organized enough to get it on time, or forgot what you said in the office, even though you wrote it down because they lost a sheet of paper it's written down on. So getting back to patient's experience of it.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

That's not using it as directed. But people with ADHD, by their very nature, are not going to use things as directed, either because they forgot or weren't organized enough to get it on time, or forgot what you said in the office, even though you wrote it down because they lost a sheet of paper it's written down on. So getting back to patient's experience of it.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

So the advantages of the immediate release is they tend to work quickly. You can feel it going in. It's easily most people, there's a lot of individual variability, but let's say in the six to eight hour range, we'll get benefit. Some shorter, some immediate release lasts all day. But you know when it's on, you know when it's off.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

So the advantages of the immediate release is they tend to work quickly. You can feel it going in. It's easily most people, there's a lot of individual variability, but let's say in the six to eight hour range, we'll get benefit. Some shorter, some immediate release lasts all day. But you know when it's on, you know when it's off.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

So the advantages of the immediate release is they tend to work quickly. You can feel it going in. It's easily most people, there's a lot of individual variability, but let's say in the six to eight hour range, we'll get benefit. Some shorter, some immediate release lasts all day. But you know when it's on, you know when it's off.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

If you forget to take your medicines in the morning, but you know you have a presentation at three that afternoon, you could take it and still be able to sleep that night. So it allows more flexibility, it allows more pinpointing of optimizing it for points the day you want to be using it.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

If you forget to take your medicines in the morning, but you know you have a presentation at three that afternoon, you could take it and still be able to sleep that night. So it allows more flexibility, it allows more pinpointing of optimizing it for points the day you want to be using it.