Dr. Joseph Fraiman

to figure out if it really helps or not, then the problem is that benefit being so small, the problem is then you only need a very small amount of harm to outweigh it.

And I can't understand why in the 1950s were we able to do a polio vaccine study with a million kids, a million children in 1950s and Jonas Salk's polio vaccine trial.

Why?

Why?

Today, our population is probably twice as large, if not more.

And we have way more money.

So what rationale is there when we were doing this in the 1950s?

Because we knew back then that was necessary.

Today, we somehow have forgotten that it is necessary to ensure our safety and especially the safety of our children.

Yes, we know better.

And this is, it's...

It's an absurdity.

And they then have, you know, they've changed the idea of saying real world evidence is there is the new term that they use for observational studies, which is everyone knows observational studies are not reliable.

And so they change it to real world.

Now it's now it's better than Iran.

It's like it's better than a randomized trial because it's called it's the real world.

And this is absurd.

I believe that we've been, our population has been tricked in a certain way on this.

And I think that it's something that, you know, I'm happy that we have people like Vinay who are kind of bringing attention to this and not only bring attention, like actually in our government, who are hopefully going to be able to get this through and actually change the standards of this.

Because I don't understand what, you know, people complaining about this, like, oh, we're not going to approve a vaccine quick enough.