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Dr. Justin Sonnenburg

๐Ÿ‘ค Speaker
281 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

good microbial community in there afterwards.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

You may not.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

You certainly want to pay close attention to what you're eating while you're doing the reconstitution of the community after you do something like that.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

For sure.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

Yeah, you're exactly right.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

And we can break down, you know, there's a lot of data of why different components of processed food are so bad for us and so bad for our microbiome.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

And I can talk about a few examples of that.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

But the flip side of this, the plant-based diet, if you're eating a bunch of complex,

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

fibers that feed your gut microbiota, your gut microbiota produces these substances called short chain fatty acids, things like butyrate.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

And it's known that these short chain fatty acids play really essential components, both in terms of fueling colonocytes

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

enforcing the barrier, keeping inflammation low, regulating the immune system, regulating metabolism.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

Your gut microbiota is just producing this vast array of fermentation end products that then get absorbed into our bloodstream and have all of these tremendous cascading effects that appear to be largely beneficial on our biology.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

Now, processed foods, I think, is this other dimension where you have all of these weird chemicals, artificial sweeteners,

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

weird fats, a lot of refined, simple nutrients.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

The simple nutrients we've talked about, but we know that, for instance, artificial sweeteners can have a massive negative impact on the gut microbiome and can lead us towards metabolic syndrome, actually.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

There's been beautiful work out of the Weizmann Institute on this.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

And then emulsifiers, these compounds that are put in processed foods to help them maintain shelf stability so things don't separate.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

all the moisture content is retained appropriately.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

Many of these are known to disrupt the mucus layer.

Huberman Lab
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

And as soon as you start disrupting that barrier, that can lead you in the direction of inflammation.