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Dr. Kevin Tracey

๐Ÿ‘ค Speaker
536 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Vagus Nerve Stimulation and the Immune System

30,000, wow.

Ground Truths
Vagus Nerve Stimulation and the Immune System

30,000 people tried to enroll in this trial for 250 spots that ended up with 242 patients in the final readout.

Ground Truths
Vagus Nerve Stimulation and the Immune System

And the reason is,

Ground Truths
Vagus Nerve Stimulation and the Immune System

and this is often overlooked when people talk about these kinds of things, the drugs are invasive.

Ground Truths
Vagus Nerve Stimulation and the Immune System

The device, I'm pulling out here.

Ground Truths
Vagus Nerve Stimulation and the Immune System

Surgery involves about an inch and a half incision in the left neck at about the level of the Adam's apple, the larynx, to implant a device that's about the size of a multivitamin.

Ground Truths
Vagus Nerve Stimulation and the Immune System

or a fish oil pill.

Ground Truths
Vagus Nerve Stimulation and the Immune System

The device sits directly on the vagus nerve at about the level of the carotid pulse.

Ground Truths
Vagus Nerve Stimulation and the Immune System

You can feel your pulse.

Ground Truths
Vagus Nerve Stimulation and the Immune System

And it is self-contained with those two shiny things are the leads that sit on the vagus nerve.

Ground Truths
Vagus Nerve Stimulation and the Immune System

There is a computer disk, of course.

Ground Truths
Vagus Nerve Stimulation and the Immune System

There's an antenna to talk to the doctor's tablet.

Ground Truths
Vagus Nerve Stimulation and the Immune System

I always drop it when I'm at the podium, and that's very complicated on stage, Eric.

Ground Truths
Vagus Nerve Stimulation and the Immune System

It also has, which is really clever, it sits on the vagus nerve, but it's wrapped in this silastic, like a peapod.

Ground Truths
Vagus Nerve Stimulation and the Immune System

And so the nerve runs underneath it, and then there's a stitch that goes through the top to hold the whole thing in place.

Ground Truths
Vagus Nerve Stimulation and the Immune System

How long did that surgery take to put it in?

Ground Truths
Vagus Nerve Stimulation and the Immune System

An experienced neurosurgeon will put it in in under an hour, anywhere between a half hour and an hour.

Ground Truths
Vagus Nerve Stimulation and the Immune System

It's an in-and-out surgery, outpatient, come in in the morning, go home in the afternoon.

Ground Truths
Vagus Nerve Stimulation and the Immune System

We've been doing them in the hospital, but obviously this will be amenable in the future to a full outpatient standalone facility.

Ground Truths
Vagus Nerve Stimulation and the Immune System

Right now, neurosurgeons are being trained by the company