Dr. Kyle Gillett

speaker

556 appearances 2 recordings 1 series first heard Dec 2025 last heard 2 Jul

Dr. Kyle Gillett’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 2 in all, peaking in Jul 2026 with 1.

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Huberman Lab · Essentials: Tools for Hormone Optimization in Males | Dr. Kyle Gillett · 2 Jul 2026 podcast

Great to be back.

Thank you.

There's many things that you should do.

An analogy that I often make is when there's a brand new car that comes off the assembly line, you do a full scope of diagnostic workup, hook it up to the computer.

And I think we should do the same thing with humans as well.

during puberty, obviously you're a functioning human, but I would say there's still development.

And I think that the human always develops.

I don't think development ever ends, but you want to monitor that progress across a person's lifespan.

And with testosterone, you want to get either testosterone and SHBG or a free testosterone.

It is sex hormone binding globulin.

It is the protein that binds up all androgens and estrogens in the body.

So the stronger the androgen, the stronger it binds.

During puberty, strong androgens, especially DHT, which is the strongest bioidentical androgen,

has a huge role, a prominent role in secondary sexual characteristics.

And if your SHBG is very high, then your DHT can run higher because it's not metabolized, but there's not quite as much free DHT.

So you want to balance between a high enough free DHT and a high enough total DHT.

Using shared decision-making with their physician.

I'll briefly touch on some of the lifestyle pillars to start.

Diet and exercise are the first two.

In puberty, sleep is particularly important, of course.

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