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Dr. Kyle Gillett

๐Ÿ‘ค Speaker
308 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

So if you're young and healthy and you don't have metabolic syndrome, then chloric restriction will likely decrease your testosterone.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

So if they're in a caloric maintenance, then it's not going to be

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

It's not gonna be deleterious.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

It's not gonna be bad for their hormone health.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

There's a couple of different hormones that we can talk about.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

We can talk about testosterone.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

We can talk about DHEA, which usually go hand in hand.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

And then we can also talk about growth hormone, which is not a steroid hormone, but it's a peptide hormone.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

So it's a chain of proteins, amino acids that are put together instead of a sterol.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Think of sterol hormones as coming from cholesterol.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

So you do get a little spike in growth hormone after you eat.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

but you also get a huge spike in growth hormone, a more significant, less negligible spike overnight.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

And that is improved if you are intermittent fasting.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

So it's probably gonna help your growth hormone and subsequently IGF-1 levels, which will help more in older age groups than younger age groups.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

There's still pretty good growth hormone output, even if you eat two or three hours before you sleep.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

It's just the law of diminishing returns.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

The longer you go, you get slightly more and slightly more.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

But I think about it in terms of endocrine IGF-1, mostly IGF-1 that's synthesized in the liver and released in the liver.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

versus IGF-1 that's released.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Classically, an example of this would be your IGF-1 levels increase after resistance training or exercise.