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Dr. Layne Norton

👤 Person
4445 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And one of my favorite phrases that I tell people, it's actually from an economist named Thomas Sowell. He said there are no solutions. There are only tradeoffs. And for example, you know, there's data out there that if you lower saturated fat, it may lower your testosterone.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And one of my favorite phrases that I tell people, it's actually from an economist named Thomas Sowell. He said there are no solutions. There are only tradeoffs. And for example, you know, there's data out there that if you lower saturated fat, it may lower your testosterone.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

But there's also data out there that saturated fat raises LDO, which is an independent risk factor for cardiovascular disease. Okay. Well, there's tradeoffs there, right? Like what do you value more? I would argue that probably the decline in testosterone isn't really physiologically meaningful for most people. But again, there's not a good or bad. There's tradeoffs.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

But there's also data out there that saturated fat raises LDO, which is an independent risk factor for cardiovascular disease. Okay. Well, there's tradeoffs there, right? Like what do you value more? I would argue that probably the decline in testosterone isn't really physiologically meaningful for most people. But again, there's not a good or bad. There's tradeoffs.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

But there's also data out there that saturated fat raises LDO, which is an independent risk factor for cardiovascular disease. Okay. Well, there's tradeoffs there, right? Like what do you value more? I would argue that probably the decline in testosterone isn't really physiologically meaningful for most people. But again, there's not a good or bad. There's tradeoffs.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And I think when people get talking about biochemical pathways, one of the things I really try to hone in on is like, hey, there's not really good or bad biochemical pathways either. Like all these things exist for a reason. Like people, like one of the things popular is like, well, inflammation, inflammation.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And I think when people get talking about biochemical pathways, one of the things I really try to hone in on is like, hey, there's not really good or bad biochemical pathways either. Like all these things exist for a reason. Like people, like one of the things popular is like, well, inflammation, inflammation.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And I think when people get talking about biochemical pathways, one of the things I really try to hone in on is like, hey, there's not really good or bad biochemical pathways either. Like all these things exist for a reason. Like people, like one of the things popular is like, well, inflammation, inflammation.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

I'm like, Hey, you know, like inflammation does some things that we really need to, like, you just don't want like no inflammation. Like it's actually important physiological process, right? Now you don't want it to run away for sure. And so again, I just give my PhD advisor a lot of credit of, he's like, know what you know, but always question yourself.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

I'm like, Hey, you know, like inflammation does some things that we really need to, like, you just don't want like no inflammation. Like it's actually important physiological process, right? Now you don't want it to run away for sure. And so again, I just give my PhD advisor a lot of credit of, he's like, know what you know, but always question yourself.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

I'm like, Hey, you know, like inflammation does some things that we really need to, like, you just don't want like no inflammation. Like it's actually important physiological process, right? Now you don't want it to run away for sure. And so again, I just give my PhD advisor a lot of credit of, he's like, know what you know, but always question yourself.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

Everything, even the things we feel most fundamentally are true, because that is the job of a good scientist. I'll give you one more story and then we'll move to another thing. When I did my first experiment, well, actually, sorry, no, this has been like my 15th experiment because my first 14 blew. It didn't work.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

Everything, even the things we feel most fundamentally are true, because that is the job of a good scientist. I'll give you one more story and then we'll move to another thing. When I did my first experiment, well, actually, sorry, no, this has been like my 15th experiment because my first 14 blew. It didn't work.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

Everything, even the things we feel most fundamentally are true, because that is the job of a good scientist. I'll give you one more story and then we'll move to another thing. When I did my first experiment, well, actually, sorry, no, this has been like my 15th experiment because my first 14 blew. It didn't work.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

Yeah, yeah. And again, very patient man, very supportive. I honestly cannot give him enough credit. And if you look at the people that came out of that lab, a lot of studs. So I did an experiment looking at complete meal with whey protein ingestion and how long the duration of muscle protein synthesis was.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

Yeah, yeah. And again, very patient man, very supportive. I honestly cannot give him enough credit. And if you look at the people that came out of that lab, a lot of studs. So I did an experiment looking at complete meal with whey protein ingestion and how long the duration of muscle protein synthesis was.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

Yeah, yeah. And again, very patient man, very supportive. I honestly cannot give him enough credit. And if you look at the people that came out of that lab, a lot of studs. So I did an experiment looking at complete meal with whey protein ingestion and how long the duration of muscle protein synthesis was.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

Because most people kind of measured at 60 or 90 minutes, like the snapshot postprandially for protein synthesis, looking for a peak. And we're like, is that really where the peak is? We don't know. We're basing this off of purified solutions. So let's do a duration experiment, right?

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

Because most people kind of measured at 60 or 90 minutes, like the snapshot postprandially for protein synthesis, looking for a peak. And we're like, is that really where the peak is? We don't know. We're basing this off of purified solutions. So let's do a duration experiment, right?

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

Because most people kind of measured at 60 or 90 minutes, like the snapshot postprandially for protein synthesis, looking for a peak. And we're like, is that really where the peak is? We don't know. We're basing this off of purified solutions. So let's do a duration experiment, right?