Dr. Luc (Luke) van Loon

No, it's a study to show that the six-hour or the four-hour response to a single meal can be longer if you give more protein because all the protein still needs to be digested and absorbed.

But that doesn't change what I think now from all the evidence that we have.

It's being advised to have a nice, even distribution of your protein in your main meals.

So the older studies, there's basically two dose response studies that show in healthy young people at rest or after exercise, 20 grams maximizes muscle protein synthesis for somewhere between four to six hours after the meal.

So in that time period, four to six hour postprandial period, we call that.

Some of that protein might not have been digested and absorbed if you give more than those 20 grams.

So the 40 grams that they showed in those studies didn't show a greater response, but they only measured for four or six hours, depending.

Now, we wanted to do a study to show that if you give 100 grams, which is

Absolutely not something that I'm suggesting that people should be consuming.

That it takes longer to digest everything and that you have a longer stimulation of muscle protein synthesis over a more prolonged period of time.

So we also measured not over six hours, but over 12 and even 24 hours.

And then we see that you get a greater response.

Now, the interesting part of this study is we also assessed digestion and absorption.

Now, that is difficult because how do you do this?

Now, instead of infusing tracers only and measuring the incorporation in muscle, that's how you measure muscle protein synthesis, we actually did an experiment before that.

We infused a cow with labeled amino acids.

So you have amino acids with a chemical flag, stable isotope labeled.

We infuse it in the cow.

The cow actually incorporates it in the milk.

So we have milk protein and we extract the milk, we extract the milk protein.