Dr. Luc (Luke) van Loon
๐ค SpeakerAppearances Over Time
Podcast Appearances
I think the greater benefits are to be expected, if they are there, on the tissues that have a higher collagen content.
And so I think there's still a window of opportunity there as a good source of glycine and proline for recovery, restoration or repair of collagen rich tissues, which could be skin, which could be tendon, cartilage, bone, etc.
Whether it is of greater benefit than the same amount of amino acids provided by other protein sources, I don't know.
But that's all stuff that we should start doing in the future.
And we are actually doing a few of those studies and we finished a few studies also where we actually looked at skin because skin is still easy to take samples from.
The other ones we can only do that pre-surgery.
So we actually take people that get a new knee and then we actually do the intervention prior to surgery.
But of course, with skin, we can take a skin biopsy and we can take a muscle biopsy repeatedly over a few hours.
And that's also stuff that we've done, but we still need to analyze everything.
So that's of interest.
And of course, it's really difficult to figure out in in vivo in humans whether this is really happening.
Because first of all, what diatri or oligopeptides are you looking for?
And then with having 20 different amino acids, you can almost have an increase
an enormous amount of different diatrin and oligopeptides.
And even if you measure them in the circulation, do they actually come from the protein that you ingested or were they newly synthesized in the liver?
So it's so difficult figuring that one out.
But it's really funny that I was in a podcast where somebody said like, how do you get along with Professor Barr from UC Davis who actually does a lot of this in vitro work
And so he must be your greatest enemy.
And I said, do you want me to pick him, to get him?
And then the guy was completely just surprised.