Dr. Luc (Luke) van Loon

That's remarkable because it's not a huge increase.

It's on the top of everything.

It's only a little increase.

Stimulus.

Now we know this from muscle, we know how it works, we know what it does, and now we have the signaling molecules, the signaling pathways, we know the mTOR, we know leucine, etc., etc.

We don't know anything about all these other tissues.

So do the other tissues respond to nutrition or not?

And that includes skin, but it also includes the liver and the heart, whatever.

So the big question is, do these tissues respond to protein ingestion by greater muscle protein synthesis, or are they just having the same turnover, but they use, of course, the amino acids that are being released by the protein in our diets?

So that's the big question.

Now, for skin, it's interesting because we can figure that one out because I can't take three samples of the liver or the lung or the brain in six hours.

That's impossible.

I can maybe obtain one sample after like a two-hour surgery.

For the skin, of course, we could actually do the same thing as muscle.

And now I'm not that much interested in skin, but if skin is actually an easier way of investigating the same process as muscle, that's interesting because then we only have to take skin biopsies, which is much easier than taking muscle biopsies.

So I'm really interested to see what comes out of that study.

But the big question is, I mean, so we've seen people, I mean, there's people doing in vitro work with all kinds of compounds, throwing them in the dish and seeing something happening.

But does the muscle see those compounds, that's one, and in what concentration?

And that's where it's limited.

So a lot of that research has not been done.