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Dr. Marc Breedlove

๐Ÿ‘ค Speaker
985 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

And that there might be a heterozygote advantage.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

I mean, you know, the classic example of sickle cell anemia, right, where being a heterozygote for that gene confers an advantage.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

If there's malaria in the area, you'll be less likely to succumb.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

Things go wrong when two copies come together in one individual, and that's when the

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

The blood cells are especially affected.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

And things go wrong when an offspring gets two such copies, which is relatively rare, but it does happen.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

And in that case, then the offspring is very sick.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

I'm certainly looking like the mad scientist.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

In fact, people do those sorts of transplants in birds.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

So a very famous neuroscientist from France, Nicole Le Duran, did these experiments where she would open up chick embryos and quail embryos, and she could scoop out part of the nervous system from one and implant it in the other.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

And she'd know when she had done it right that she had a way of

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

telling the cells apart under a microscope.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

Plus when they grew up, here you'd have this white leghorn chicken with a streak of brown feathers right where she... Was it called a quicken?

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

Sorry, couldn't help myself.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

Here you'd have this white leghorn chicken with a streak of brown feathers in the middle that were derived from the quail.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

And so it is possible to do those sorts of swaps.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

And of course, this is what's so great about working with birds is their embryos are...

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

you know, easy to get to for the first 21 days or so.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

So people had done those sorts of experiments.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

There was a question about sexual differentiation of the brain in birds because the, and I'll tell you why it turned out I didn't need to do that experiment and it wouldn't have shown what we wanted.