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Dr. Marc Breedlove

๐Ÿ‘ค Speaker
985 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

That is, so there are, sometimes you'll see in the news, someone will find a genandromorph.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

In birds, yep.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

Ginandromorphs.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

So half female, gin, and half male, andro.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

And when it happens in cardinals, for example, it's like the animal's been split down the middle.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

No.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

Yes, where the one side is the bright red of a male with a crest, et cetera, and the other side isn't.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

Right?

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

So these occur occasionally.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

And our best understanding of what happened there, first of all, the sex chromosome is a little different in birds than mammals.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

I'm going to gloss over that.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

But our best understanding of what happened there is this is a case where two embryos, one that was carrying male sex chromosomes and the other female sex chromosomes,

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

came together at an early stage.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

And so what we have is a mosaic animal where one side is genetically male and the other side is genetically female.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

Now, in a mammal, if that happened, the testis on the male side would masculinize everything by using hormones.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

The clue that something else is going on

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

in birds is that in this case, there's not been this blending.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

And when Art Arnold and others looked at the brains of genandromorphs, sure enough, the sex differences where this region, HVC, for example, tends to be larger in males than in females.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

In these animals, it was larger on one side of the body than on the other.

Huberman Lab
How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

So they were indeed