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Dr. Mark D'Esposito

๐Ÿ‘ค Speaker
869 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

It's only as long as you're able to rehearse it, and then it disappears, whereas what we call long-term memory, if you're remembering what you had for breakfast or your vacation, this is information that gets consolidated and gets put into a

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

a more durable form that we call long-term memory.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And the interesting thing about memory is that these are separate systems.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Everything from working memory just doesn't pass into long-term memory.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

They're two completely different systems and two completely different parts of the brain that seem to control it.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So working memory, the frontal cortex seems to be very important for working memory.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

When we are holding information in line, the neurons, the brain cells in the frontal lobes

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

are active and they stay kind of active as long as we're holding on that information.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And they're more active when the information is relevant.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And if we we get distracted, they'll get less active.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So kind of the frontal lobes kind of track your

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

you know, track the memory that you're holding in mind.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Another important thing about the circuitry is that if we're holding in mind, say, digits, you know, the phone number, well, that information is in your back of the brain.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And so the frontal lobes is sort of keeping information in the back of the brain active because it's connected to the visual areas.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

It's able to sort of keep that information active.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And so what we've learned is that there's not these buffers in the brain.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

where if you're holding verbal information, it's in this little buffer, and if you're holding visual information, it's in another buffer.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

The whole brain acts as a buffer, and the frontal lobe can call up any part of the brain and keep that part of the brain active as it's

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

as it's trying to hold this information in line.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So the mechanism for working memory is just this persistent neural activity within the frontal lobes.