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Dr. Mark D'Esposito

๐Ÿ‘ค Speaker
869 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And there's a number of psychiatric disorders, obsessive-compulsive disorder, and schizophrenia and depression that are thought to be frontal lobe dysfunction.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

But when you're sleep-deprived and when you're stressed and just normal aging, the frontal lobe seems to be the first system that's affected because it really is involved in the highest level.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So when we're having a bad day, when we're having difficulties sort of setting priorities, when we're having difficulties achieving goals

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

the goal that we've set out.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

When we get distracted, you know, when we're not able to sort of adapt and be flexible, these are all the type of things that reflect that our frontal lobes are not functioning optimally.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah, I mean, it's a really tough question to know when they're fully developed because these studies haven't been done.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

When MRI was introduced and we were able to sort of image the brain in a non-invasive way, then studies did start to come out trying to sort of map out at what age does your frontal lobes fully develop.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And it seemed like it was early into your 20s.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

You know, I always say that it's not surprising that you can't rent a car until you're 25.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

The insurance companies knew before, neuroscientists did, as to when your frontal lobes have, you know, when your decision-making skills

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

at their highest.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And so that's probably about right into your 20s is probably before your frontal lobes are fully developed.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And it's really interesting question is why does it take so long?

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

It's the area of the brain that takes the longest to develop and why is that?

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And I think there's a reason.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

I think that this sort of slow development of frontal lobes allows us to explore, allows us to think about novel ways of solving problems, allows us to take in

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

the world, if they were shut off earlier, it would lead to maybe a much more sort of rigid kind of, you know, less flexible kind of behavior that we've seen things.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So I think that it helps to take a long time to develop, but also it obviously leads to some problems sometimes in adolescence as we see sometimes.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah, it's hard to say.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

I mean, the frontal lobe is a big territory, and we can get into it.