Dr. Mark D'Esposito

It doesn't yet, I don't think we know enough about how we should tailor the mindfulness, but most forms of mindfulness will work of the type you're talking about.

No, I think that's one of the things when we're talking about what should we do besides reading fiction.

I think that should be on my list.

Five minutes a day.

No, I guess it's just amazing that the patients tell me about it and what we've seen from our studies.

You know, a lot of this, like again I was saying before, is if we had some measure of, you know, brain health that we could see the impact of it would sort of push us towards, you know, probably doing it more.

I think another thing that we didn't sort of talk about, we talked a little about what dopamine is, are there other kind of brain states that sort of, you know, predict, you know, how you're going to respond to these therapies and if you're going to benefit from them.

You know, we've done a lot of work with sort of measuring sort of the large-scale organization of the brain and brain networks, and that's sort of a very popular idea in neuroscience today, sort of moving away from sort of what is this... We've talked a lot about what the frontal lobes do, but the frontal lobes are part of these networks in the brain, and...

really sort of the state of your networks is really an important factor as well, in addition to sort of your neurochemical profile.

Well, in the grand scale, I'm excited that things that we've learned over the last 30 years, not just in my lab or your lab or anyone's lab is actually now being translated to actually helping people.

I mean, when people ask me what I do, I say I'm a neurologist because that's at my core, what I feel I am.

And I feel I got into this business to,

They help people.

And so it's when you work for years and years and years and it doesn't translate, it can be frustrating.

But now I'm excited that it seems that the things we've learned, that all of us have learned in neuroscience is starting to now translate into something different.

In neuroscience, what's happened in the last 10 years, we're thinking of the brain in a kind of grander scale.

It's overall organization, not so focused on just this area or that area.

When I talk about the frontal lobes as being the most important part, the conductor...

Yes, I am talking about one brain region, but it's a brain region, like I said, that's connected to everywhere.

And it's because it's connected to everywhere is what's really the essence of why it's so important.