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Dr. Mark D'Esposito

πŸ‘€ Speaker
869 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And so we have a different target to go after for treatments.

7809.922 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

What can we do to sort of boost, you know, a hub that's been damaged as opposed to thinking about it in a...

7813.308 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

in a less specific way.

7820.26 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And then also, as we really start to learn about how the brain is organized in these networks, we've also learned that measuring your network structure is very predictive of your well-being and how you respond to interventions.

7821.903 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So there's a metric called modularity.

7838.599 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

which measures how organized your brain networks are.

7841.168 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And the brain is made up of different modules, different networks.

7845.812 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And these networks can either be very communicating with each other or not so communicating with each other.

7850.316 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And the more segregated they are, we call that more modularity.

7855.321 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

They're kind of separate entities.

7860.446 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

They're modular.

7862.708 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And it turns out we can measure that with fMRI.

7864.569 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

We can put someone in the scanner.

7866.912 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

We can do this resting thing.

7868.553 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

fMRI scanning and then we can measure how modular your brain is versus my brain and all of us are very

7870.885 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

different levels of modularity.

7877.028 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah, it turns out that it seems to be more advantageous to have more.

7882.915 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So we can predict... More separateness of brain function between areas.

7885.718 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah, that the networks are sort of more independent.

7889.603 View full episode β†’
Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

That doesn't mean they don't talk to each other, but at sort of baseline, they're more independent.

7892.326 View full episode β†’