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Dr. Mark D'Esposito

๐Ÿ‘ค Speaker
869 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And so we have a different target to go after for treatments.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

What can we do to sort of boost, you know, a hub that's been damaged as opposed to thinking about it in a...

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

in a less specific way.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And then also, as we really start to learn about how the brain is organized in these networks, we've also learned that measuring your network structure is very predictive of your well-being and how you respond to interventions.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So there's a metric called modularity.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

which measures how organized your brain networks are.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And the brain is made up of different modules, different networks.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And these networks can either be very communicating with each other or not so communicating with each other.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And the more segregated they are, we call that more modularity.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

They're kind of separate entities.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

They're modular.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And it turns out we can measure that with fMRI.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

We can put someone in the scanner.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

We can do this resting thing.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

fMRI scanning and then we can measure how modular your brain is versus my brain and all of us are very

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

different levels of modularity.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah, it turns out that it seems to be more advantageous to have more.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So we can predict... More separateness of brain function between areas.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah, that the networks are sort of more independent.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

That doesn't mean they don't talk to each other, but at sort of baseline, they're more independent.