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Dr. Mark D'Esposito

๐Ÿ‘ค Speaker
869 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

But that's very different than what's your baseline modularity.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Because you've got to get from your

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

your you know where your baseline is to this other state and a lot of it has to do is like going from one state to another not not so much sort of the absolute sort of differences so that's that's interesting i didn't know about those results but it's interesting that uh that it does affect sort of connectivity in that way i think the drugs that are going to be helpful are going to are going to promote sort of networks talking to each other as opposed to networks not communicating with each other

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah, so I think, you know, I have a lot of patients that I've referred for its approved use, which is depression.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So I'm very excited about sort of the work that's being done for depression.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

But we haven't really had any improved anything that's been for, you know, for cognition.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So there are a bunch of studies, anecdotal small studies, where you can give transcranial maxillofacial stimulation, frontal cortex, and working memory improved.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

But they really haven't been done in ways that are

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

We don't know if it generalizes, if it's going to be how, you know, the way it's been done in depression in a way that can really be.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

But again, it's just a matter of doing it.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

I think it will be part of the things we do, drugs, TMS, and all the other things we've talked about.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

It's not just going to be one thing.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And it gets back to networks, right?

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

What this is doing is really changing how nodes, you know, the interaction of regions.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

It's not about sort of just increasing or decreasing activity in some regions.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

mysterious part of the brain.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

It's this sort of restoring the balance of a network.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Well, I'd say, you know, on behalf of all the neurologists in the world, thank you for appreciating what we do.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

It's just so important to try and get this message apart.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Like I said, you know, with patients, we just try to have them understand what it is that they're going through.