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Dr. Mark D'Esposito

๐Ÿ‘ค Speaker
869 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So we're not, I guess another way of saying it, just having knowledge isn't what makes us who we are, right?

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

It's to be able to take that knowledge and present it in a way that allows us to live life based on our intentions and our goals and our desires.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah, I mean, as I was saying earlier, the frontal lobes is a big place, and half of it is involved in these high-level executive functions, but the other half of it is part of the limbic system.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

We call it the paralimic system that's involved in social and emotional behavior.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

there's this intimate back and forth between these two areas of the cortex.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

If you have just damage to these frontal, to these areas that are kind of in the frontal lobe, you will have

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

many different impairments that we would call sort of social or emotional impairments, and their executive function will be quite normal.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And then you'll have the opposite where patients with the lateral damage will have executive functions, but they seem emotionally intact.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

But, you know, in real life, when we have both these intact, they're communicating with each other.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So, right, emotion and contacts is going to influence our

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

executive function.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

We make bad decisions in stressful situations or situations we're not comfortable with.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

It's where we might make a better decision if it's a quiet, you know, kind of a quiet place.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

But it is something that we can, I think you're right, you can sort of get into a routine and learn how to do things, you know, if you haven't very much planned out.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

But what's so unique about us is how we can be flexible and adaptable, right?

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

When

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

When something novel comes up or there's something unexpected comes up, we can adapt to it.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And that's really what the frontal cortex is really important for, not just sort of making these plans, routines, and setting all the rules, but being able, when things don't go right, how to right the ship, right?

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah, I mean, I can, you know, just historically, I grew up in a world when there was no smartphones as a resident.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And so one of the most difficult things I do in practice is have to take care of patients in the emergency room and there's a real emergency.